5-(Bromomethyl)-7-methoxy-2H-chromen-2-one

Base Information

Chemical Name:5-(Bromomethyl)-7-methoxy-2H-chromen-2-one
CAS No.:54745-57-2
Molecular Formula:C11H9BrO3
Molecular Weight:269.09100
Hs Code.:2932209090
DSSTox Substance ID:DTXSID50471443
Wikidata:Q82299950
Mol file:54745-57-2.mol

Synonyms:5-(Bromomethyl)-7-methoxy-2H-chromen-2-one;54745-57-2;5-(BROMOMETHYL)-7-METHOXYCHROMEN-2-ONE;5-Brommethyl-7-methoxycoumarin;DTXSID50471443;5-(Bromomethyl)-7-methoxy-2H-1-benzopyran-2-one

Suppliers and Price of 5-(Bromomethyl)-7-methoxy-2H-chromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Bromomethyl)-7-methoxy-2H-chromen-2-one 95+%
1g
$ 581.00

Chemenu
5-(bromomethyl)-7-methoxy-2H-chromen-2-one 95%
1g
$ 549.00

Alichem
5-(Bromomethyl)-7-methoxy-2H-chromen-2-one
1g
$ 511.92

Total 1 raw suppliers

Chemical Property of 5-(Bromomethyl)-7-methoxy-2H-chromen-2-one

Chemical Property:

PSA：39.44000
LogP:2.69650
Storage Temp.:2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:267.97351
Heavy Atom Count:15
Complexity:277

Purity/Quality:: 5-(Bromomethyl)-7-methoxy-2H-chromen-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C2C=CC(=O)OC2=C1)CBr

Technology Process of 5-(Bromomethyl)-7-methoxy-2H-chromen-2-one

There total 4 articles about 5-(Bromomethyl)-7-methoxy-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 53666-74-3
7-methoxy-5-methyl-2H-chromen-2-one

: 54745-57-2
5-(bromomethyl)-7-methoxy-2H-chromen-2-one

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; Heating;
DOI:10.1021/jm049535j

Reference yield:

: 504-15-4
orcinol

: 54745-57-2
5-(bromomethyl)-7-methoxy-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: 120 °C

1.2: 70 percent / H₂SO₄; CF₃COOH / 3 h / 20 °C

2.1: NaH / dimethylformamide / 0.33 h / 0 °C

2.2: 62 percent / NaH / dimethylformamide / 5 h / 0 - 20 °C

3.1: 51 percent / N-bromosuccinimde; benzoyl peroxide / CCl₄ / Heating

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm049535j

Reference yield:

: 7249-26-5
7-hydroxy-5-methyl-chromen-2-one

: 54745-57-2
5-(bromomethyl)-7-methoxy-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.33 h / 0 °C

1.2: 62 percent / NaH / dimethylformamide / 5 h / 0 - 20 °C

2.1: 51 percent / N-bromosuccinimde; benzoyl peroxide / CCl₄ / Heating

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm049535j