3-(Hydroxymethyl)-2-methylphenol

Base Information

• Chemical Name: 3-(Hydroxymethyl)-2-methylphenol
• CAS No.: 54874-26-9
• Molecular Formula: C8H10O2
• Molecular Weight: 138.166
• Hs Code.: 2907299090
• DSSTox Substance ID: DTXSID90516726
• Wikidata: Q82378274
• Mol file: 54874-26-9.mol

Synonyms:3-(HYDROXYMETHYL)-2-METHYLPHENOL;54874-26-9;cresol-methanol;3-Hydroxymethyl-2-methyl-phenol;3-hydroxy-2-methylbenzyl alcohol;SCHEMBL286623;3-hydroxymethyl-2-methylphenol;AMY169;3-hydroxymethyl-2-methyl phenol;DTXSID90516726;QWFILMGCTBJAQQ-UHFFFAOYSA-N;ZB0018;AKOS006286746;CS-0130612;FT-0746223;A870337

Chemical Property of 3-(Hydroxymethyl)-2-methylphenol

Chemical Property:

• PSA: 40.46000
• LogP: 1.19290
• Storage Temp.: 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 138.068079557
• Heavy Atom Count: 10
• Complexity: 103

Purity/Quality:

97% ^*data from raw suppliers

3-(Hydroxymethyl)-2-methylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC=C1O)CO

Technology Process of 3-(Hydroxymethyl)-2-methylphenol

There total 1 articles about 3-(Hydroxymethyl)-2-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-hydroxy 2-methylbenzoic acid (603-80-5) → 3-hydroxymethyl-2-methylphenol (54874-26-9)

Guidance literature:

3-hydroxy 2-methylbenzoic acid; With borane-THF; In tetrahydrofuran; at 20 ℃;

With water; sodium hydrogencarbonate; In tetrahydrofuran;

Reference yield: 96.0%

bromoacetic acid tert-butyl ester (5292-43-3) + 3-hydroxymethyl-2-methylphenol (54874-26-9) → (3-hydroxymethyl-2-methylphenoxy)acetic acid tert-butyl ester

Guidance literature:

With potassium carbonate; In acetone; for 40h; Heating / reflux;

Reference yield: 95.0%

isopropyl 2-bromoacetate (29921-57-1) + 3-hydroxymethyl-2-methylphenol (54874-26-9) → Isopropyl 2-[3-(hydroxymethyl)-2-methylphenoxy]acetate (1310698-28-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

3-hydroxy 2-methylbenzoic acid

Downstream raw materials:

[2-methyl-3-(pyridin-2-yloxy)-phenyl]-methanol

6-bromo-3-hydroxy-2-methylbenzenemethanol

Isopropyl 2-[3-(hydroxymethyl)-2-methylphenoxy]acetate

4-methyl-5-[2R-oxiran-2-yl]-2-benzofuran-1(3H)-one