Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-

Base Information

Chemical Name:Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-
CAS No.:100199-60-8
Molecular Formula:C12H14 N2 O2
Molecular Weight:218.2518
Hs Code.:
European Community (EC) Number:834-119-1
DSSTox Substance ID:DTXSID20143004
Nikkaji Number:J1.992.965E
Wikidata:Q83006643
Mol file:100199-60-8.mol

Synonyms:Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-;100199-60-8;[4-(2-imidazol-1-ylethoxy)phenyl]methanol;MR 948;N-(2-(p-Hydroxymethylphenoxy)ethyl)imidazole;4-(2-(1H-Imidazol-1-yl)ethoxy)benzenemethanol;DTXSID20143004;LS-30775;4-[2-(1H-Imidazole-1-yl)ethoxy]benzenemethanol;EN300-6731231;{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}methanol

Suppliers and Price of Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-

Chemical Property:

Vapor Pressure:2.29E-09mmHg at 25°C
Boiling Point:462.9°Cat760mmHg
Flash Point:233.7°C
Density:1.16g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:194

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CO)OCCN2C=CN=C2

Technology Process of Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-

There total 3 articles about Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 75912-98-0
methyl 4-<2-(1H-imidazol-1-yl)-ethoxy>-benzoate

: 100199-60-8
[4-(2-imidazol-1-yl-ethoxy)-phenyl]-methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 17h; Heating;
DOI:10.1016/j.tetlet.2003.10.198

Reference yield:

: 3204-73-7
4-(2-hydroxyethoxy)benzoic acid methyl ester

: 100199-60-8
[4-(2-imidazol-1-yl-ethoxy)-phenyl]-methanol

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / SOCl₂; pyridine / 3 h / Heating

2: 60 percent / NaH / dimethylformamide / 16 h / 100 °C

3: 88 percent / LAH / tetrahydrofuran / 17 h / Heating

With pyridine; lithium aluminium tetrahydride; thionyl chloride; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2003.10.198

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 100199-60-8
[4-(2-imidazol-1-yl-ethoxy)-phenyl]-methanol

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / KOH; [Bmim][PF₆] / 12 h / 80 °C

2: 80 percent / SOCl₂; pyridine / 3 h / Heating

3: 60 percent / NaH / dimethylformamide / 16 h / 100 °C

4: 88 percent / LAH / tetrahydrofuran / 17 h / Heating

With pyridine; potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; sodium hydride; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2003.10.198