Benzofuran, 5-bromo-2,3-diphenyl-

Base Information

• Chemical Name: Benzofuran, 5-bromo-2,3-diphenyl-
• CAS No.: 55082-66-1
• Molecular Formula: C20H13BrO
• Molecular Weight: 349.227
• DSSTox Substance ID: DTXSID80484985
• Wikidata: Q82323818
• Mol file: 55082-66-1.mol

Synonyms:55082-66-1;5-Bromo-2,3-diphenylbenzofuran;Benzofuran, 5-bromo-2,3-diphenyl-;SCHEMBL1819136;DTXSID80484985;5-Bromo-2,3-diphenyl-Benzofuran;FT-0778000

Chemical Property of Benzofuran, 5-bromo-2,3-diphenyl-

Chemical Property:

• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 348.01498
• Heavy Atom Count: 22
• Complexity: 359

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(OC3=C2C=C(C=C3)Br)C4=CC=CC=C4

Technology Process of Benzofuran, 5-bromo-2,3-diphenyl-

There total 8 articles about Benzofuran, 5-bromo-2,3-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,3-diphenylbenzofuran (13054-95-0) → 5-bromo-2,3-diphenylbenzofuran (55082-66-1)

Guidance literature:

With bromine; In tetrachloromethane; for 1h;

Reference yield: 80.0%

4-bromo-phenol (106-41-2) + (Z)-1-methylsulphinyl-1,2-diphenylethene (73774-47-7) → 5-bromo-2,3-diphenylbenzofuran (55082-66-1)

Guidance literature:

With trifluoroacetic anhydride; In dichloromethane; at 25 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

DOI:10.1246/bcsj.20180321

Reference yield: 79.0%

4-bromo-phenol (106-41-2) + diphenyl acetylene (501-65-5) → 5-bromo-2,3-diphenylbenzofuran (55082-66-1)

Guidance literature:

With oxygen; copper(II) bis(trifluoromethanesulfonate); zinc(II) chloride; In nitrobenzene; at 120 ℃; for 24h; Schlenk technique;

DOI:10.1039/c3cc42326c

upstream raw materials:

2-hydroxy-2-phenylacetophenone

phenol

2,3-diphenylbenzofuran

4-bromo-phenol

Downstream raw materials:

C₂₆H₂₅BO₃

C₅₀H₃₂O