O-Methyl-L-tyrosine phenylmethyl ester

Base Information

Chemical Name:O-Methyl-L-tyrosine phenylmethyl ester
CAS No.:55456-41-2
Molecular Formula:C17H19NO3
Molecular Weight:285.343
Hs Code.:
DSSTox Substance ID:DTXSID101281854

Synonyms:55456-41-2;O-Methyl-L-tyrosine phenylmethyl ester;SCHEMBL7270126;JYRNVSKKZGIZOA-INIZCTEOSA-N;DTXSID101281854;Benzyl (S)-2-amino-3-(4-methoxyphenyl)propanoate;2(S)-amino-3-(4-methoxy-phenyl)-propionic acid benzyl ester

Suppliers and Price of O-Methyl-L-tyrosine phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of O-Methyl-L-tyrosine phenylmethyl ester

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:285.13649347
Heavy Atom Count:21
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC(C(=O)OCC2=CC=CC=C2)N
Isomeric SMILES:COC1=CC=C(C=C1)C[C@@H](C(=O)OCC2=CC=CC=C2)N

Technology Process of O-Methyl-L-tyrosine phenylmethyl ester

There total 5 articles about O-Methyl-L-tyrosine phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 137992-25-7
N-t-butoxycarbonyl-O-methyl-L-tyrosine benzyl ester

: 55456-41-2
(S)-benzyl 2-amino-3-(4-methoxyphenyl)propanoate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 2h;

Reference yield:

: 53267-93-9
O-methyl-N-tert-butoxycarbonyl-L-tyrosine

: 55456-41-2
(S)-benzyl 2-amino-3-(4-methoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

With caesium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.8b01201

Reference yield:

: 100-39-0
benzyl bromide

: 55456-41-2
(S)-benzyl 2-amino-3-(4-methoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

With caesium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.8b01201