7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one

Base Information

Chemical Name:7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one
CAS No.:55469-90-4
Molecular Formula:C9H10N2O
Molecular Weight:162.18800
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50480494
Wikidata:Q82315291
Mol file:55469-90-4.mol

Synonyms:7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one;55469-90-4;7-methyl-2,3-dihydro-1H-1,8-naphthyridin-4-one;MFCD09834139;SCHEMBL4241202;DTXSID50480494;JRMULBRHYILQJJ-UHFFFAOYSA-N;AKOS006327492;AC-6359;AS-39038;SY226808;CS-0101117;A830660

Suppliers and Price of 7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one
100mg
$ 200.00

Labseeker
7-methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one 95
1g
$ 1083.00

Crysdot
7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one 95+%
250mg
$ 238.00

Crysdot
7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one 95+%
1g
$ 595.00

American Custom Chemicals Corporation
7-METHYL-2,3-DIHYDRO-1,8-NAPHTHYRIDIN-4-(1H)-ONE 95.00%
5MG
$ 505.08

Alichem
7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one
5g
$ 2040.20

Alichem
7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one
1g
$ 733.57

Total 12 raw suppliers

Chemical Property of 7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:154-156 °C(Solv: ethanol (64-17-5))
Boiling Point:341.721oC at 760 mmHg
PKA:6.74±0.40(Predicted)
Flash Point:160.467oC
PSA：41.99000
Density:1.173g/cm3
LogP:1.52630
Storage Temp.:2-8°C(protect from light)
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C=C1)C(=O)CCN2

Technology Process of 7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one

There total 6 articles about 7-Methyl-2,3-dihydro-1,8-naphthyridin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 1824-81-3
2-Amino-6-methylpyridine

: 140-88-5,9003-32-1
ethyl acrylate

: 55469-90-4
7-methyl-2,3-dihydro-1,8-naphthyridin-4-(1H)one

Guidance literature:: 2-Amino-6-methylpyridine; ethyl acrylate; With acetic acid; at 150 ℃; for 50h;

With sodium hydroxide; at 20 - 120 ℃; for 1h;

Reference yield:

: 55469-89-1
N-(6-methyl-[2]pyridyl)-β-alanine

: 55469-90-4
7-methyl-2,3-dihydro-1,8-naphthyridin-4-(1H)one

Guidance literature:: N-(6-methyl-[2]pyridyl)-β-alanine; With chlorosulfonic acid; In dichloromethane; at 20 ℃; for 2h; Cooling with ice;

With sodium carbonate; sodium hydroxide; In dichloromethane; water; pH=~ 6 - ~ 11;

Reference yield:

: 1824-81-3
2-Amino-6-methylpyridine

: 55469-90-4
7-methyl-2,3-dihydro-1,8-naphthyridin-4-(1H)one

Guidance literature:: Multi-step reaction with 3 steps

1.1: 50 h / 150 °C

2.1: sodium hydroxide; water / 1 h / 20 - 120 °C

2.2: pH ~ 4 - ~ 5 / Cooling with ice

3.1: chlorosulfonic acid / dichloromethane / 2 h / 20 °C / Cooling with ice

3.2: pH ~ 6 - ~ 11

With chlorosulfonic acid; water; sodium hydroxide; In dichloromethane;