4-Bromo-2-methylbut-2-enoic acid ethyl ester

Base Information

Chemical Name:4-Bromo-2-methylbut-2-enoic acid ethyl ester
CAS No.:55514-49-3
Molecular Formula:C7H11BrO2
Molecular Weight:207.067
Hs Code.:
European Community (EC) Number:611-279-9
DSSTox Substance ID:DTXSID101278247

Synonyms:55514-49-3;4-bromo-2-methylbut-2-enoic acid ethyl ester;SCHEMBL4778252;DTXSID101278247;Ethyl (2E)-4-bromo-2-methyl-2-butenoate

Suppliers and Price of 4-Bromo-2-methylbut-2-enoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Bromo-2-methylbut-2-enoic acid ethyl ester

Chemical Property:

Vapor Pressure:0.105mmHg at 25°C
Boiling Point:221.8oC at 760 mmHg
Flash Point:87.9oC
PSA：26.30000
Density:1.343g/cm3
LogP:1.89070
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:205.99424
Heavy Atom Count:10
Complexity:141

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=CCBr)C
Isomeric SMILES:CCOC(=O)/C(=C/CBr)/C

Technology Process of 4-Bromo-2-methylbut-2-enoic acid ethyl ester

There total 12 articles about 4-Bromo-2-methylbut-2-enoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 50471-46-0
ethyl 2-methyl-2-hydroxy-3-butenoate

: 55514-49-3
ethyl (E)-γ-bromo-α-methylbut-2-enoate

Guidance literature:: With phosphorus tribromide; at 5 - 15 ℃; for 4h; Temperature;

Reference yield: 92.0%

: 90177-85-8
4-hydroxy-2-methylbut-2-enoic acid ethyl ester

: 55514-49-3
ethyl (E)-γ-bromo-α-methylbut-2-enoate

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 20 - 26 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2010.03.093

Reference yield: 40.0%

: 5837-78-5,55514-48-2
Ethyl tiglate

: 55514-49-3
ethyl (E)-γ-bromo-α-methylbut-2-enoate

Guidance literature:: Ethyl tiglate; With chloro-trimethyl-silane; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

With N-Bromosuccinimide; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2019.05.060