50471-46-0

Usage

Uses

Used in Agricultural Industry:
Ethyl 2-hydroxy-2-methyl-but-3-enoate is used as an intermediate in the synthesis of Vinclozolin (V314050), which is an agricultural fungicide. Vinclozolin is effective in controlling a wide range of fungal diseases in various crops, thereby protecting them from yield losses and ensuring food security.
In the synthesis of Vinclozolin, Ethyl Vinyllactate plays a crucial role as a precursor, contributing to the development of this important fungicide. Its presence in the synthesis process highlights the significance of Ethyl Vinyllactate in the agricultural industry, where it helps in the production of effective and widely used crop protection agents.

Upstream product

• 1647-12-7 ethyl 2-methyl-but-3-enoate 
• 617-35-6 2-oxo-propionic acid ethyl ester 
• 1826-67-1 vinyl magnesium bromide 
• 3536-96-7 vinylmagnesium chloride 
• 74-90-8 hydrogen cyanide 
• 78-94-4 methyl vinyl ketone 
• 64-17-5 ethanol 
• 31572-04-0 2-hydroxy-2-methylbuten-3-oic acid 

Downstream Products

• 51263-63-9 Ethyl esters of 4-bromoisoangelic acid + 4-bromoangelic acid 
• 122009-11-4 ethyl 4-diethoxyphosphono-2-methyl-2-butenoate 
• 55514-49-3 ethyl (E)-γ-bromo-α-methylbut-2-enoate 

Relevant academic research and scientific papers

4 - Halogenated -2 - methyl -2 - butenoic acid ethyl ester and preparation method thereof

The invention discloses 4 - halogenated -2 - methyl -2 - butenoic acid ethyl ester and a preparation method thereof, and particularly relates to the technical field of chemical intermediate synthesis. The 4 -halogenated -2 -methyl -2 - butenoic acid ethyl ester comprises the following steps: 2 - methyl -3 - butenoic acid ethyl ester is oxidized to synthesize 2 - methyl -2 -hydroxy -3 -butenoic acid ethyl ester. The 2 -methyl -2 -hydroxy -3 -butenoic acid ethyl ester is halogenated to give 4 -halo -2 - methyl -2 -butenoic acid ethyl ester. The synthesis method is simple, the yield is high, the use of toxic liquid bromine and hydrocyanic acid is avoided, and industrial production is easy.

4-halo-2-methyl-2-butenoic acid ethyl ester preparation method

The invention discloses a 4-halogenated-2-methyl-2-ethyl crotonate preparing method which includes following steps: (1) performing a Grignard reaction to ethyl pyruvate (II) and a vinyl magnesium halide Grignard reagent (III) to obtain a condensation compound (IV) after the reaction finished, and carrying out a hydrolysis reaction to the condensation compound (IV) to obtain a hydroxyl compound (V); and (2) performing a halogenating reaction to the hydroxyl compound and a haloid acid to obtain the 4-halogenated-2-methyl-2-ethyl crotonate (I). The 4-halogenated-2-methyl-2-ethyl crotonate preparing method is simple in total technology, allows raw materials to be obtained easily, is good in reaction selectivity, is less in by-products and is high in yield. The employed raw materials are all low-toxic or toxic-free and are all corrosiveness-free so that the method is not rigorous in requirement of devices, is environmental-friendly and is suitable for industrialized production.

Preparation of alkenyl-lactic acid esters and the novel esters obtained

A process for the preparation of an alkenyl-lactic acid ester by reaction of a cyanohydrin with an alcohol in the presence of hydrogen chloride, followed by hydrolysis. The compounds obtained may be used for the preparation of alkaloids and crop protection agents, and as monomers for copolymerization.