Fmoc-D-2-(5-bromothienyl)alanine

Base Information

• Chemical Name: Fmoc-D-2-(5-bromothienyl)alanine
• CAS No.: 220497-83-6
• Molecular Formula: C₂₂H₁₈BrNO₄S
• Molecular Weight: 472.359
• Hs Code.: 29223900
• DSSTox Substance ID: DTXSID801130977
• Mol file: 220497-83-6.mol

Synonyms:Fmoc-D-2-(5-bromothienyl)alanine;220497-83-6;Fmoc-D-alpha-(5-bromothienyl)alanine;(2R)-3-(5-bromothiophen-2-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid;Fmoc-3-(5-bromothien-2-yl)-D-alanine;DTXSID801130977;MFCD01311772;AKOS037655580;(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromothiophen-2-yl)propanoic acid;PS-12523;CS-0179070;A50227;Fmoc-D-2-(5-bromothienyl)alanine, AldrichCPR;J-014447;Fmoc-D-2-(5-bromothienyl)alanine (Fmoc-D-2Thi(5-Br)-OH);(alphaR)-5-Bromo-alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid

Chemical Property of Fmoc-D-2-(5-bromothienyl)alanine

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 3.31E-18mmHg at 25°C
• Melting Point: 158.1 °C
• Boiling Point: 657.9 °C at 760 mmHg
• Flash Point: 351.7 °C
• PSA: 103.87000
• Density: 1.528 g/cm³
• LogP: 5.43590
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 471.01399
• Heavy Atom Count: 29
• Complexity: 583

Purity/Quality:

98%Min ^*data from raw suppliers

Fmoc-d-2-(5-bromothienyl)alanine ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=C(S4)Br)C(=O)O
• Isomeric SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@H](CC4=CC=C(S4)Br)C(=O)O

Technology Process of Fmoc-D-2-(5-bromothienyl)alanine

There total 1 articles about Fmoc-D-2-(5-bromothienyl)alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

→ (2S)-3-(5-bromothiophene-2-yl)-2-(9H-fluorene-9-ylmethoxycarbonylamino)propanoic acid (220497-50-7,220497-83-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; at 20 ℃; for 1h;

Refernces