Chemical Products List

FMOC-amino acid

FMOC-amino acids are amino acids where the amino group (-NH2) is protected by a 9-fluorenylmethoxycarbonyl (FMOC) group. This protection is essential in peptide synthesis to prevent unwanted reactions with other reagents or functional groups during the coupling steps. FMOC-amino acids are synthesized by reacting the amino acid with FMOC-Cl (FMOC chloride), resulting in the formation of the FMOC-protected amino acid. In peptide synthesis, FMOC-amino acids serve as building blocks for assembling peptides and proteins on solid-phase supports. The FMOC group is selectively removed under basic conditions (such as piperidine in DMF), exposing the free amino group for the next coupling reaction. FMOC-amino acids are favored in peptide synthesis due to their stability, compatibility with automated peptide synthesizers, and ease of cleavage from the resin after synthesis. They are widely used in research and industrial settings to produce peptides and proteins for applications in biotechnology, pharmaceuticals, and biochemical research.