2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-

Base Information

Chemical Name:2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-
CAS No.:116731-95-4
Molecular Formula:C17H15 Cl2 N O
Molecular Weight:320.218
Hs Code.:
DSSTox Substance ID:DTXSID40151484
Nikkaji Number:J356.839C
Wikidata:Q76280518

Synonyms:trans-3-(3,4-Dichlorophenyl)-4-phenyl-2-piperidinone;2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-;116731-95-4;SCHEMBL10684465;DTXSID40151484;LS-117243;3alpha-(3,4-Dichlorophenyl)-4beta-phenylpiperidin-2-one

Suppliers and Price of 2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-

Chemical Property:

Vapor Pressure:5.59E-10mmHg at 25°C
Boiling Point:496.1°Cat760mmHg
Flash Point:253.8°C
Density:1.274g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:319.0530695
Heavy Atom Count:21
Complexity:370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC(=O)C(C1C2=CC=CC=C2)C3=CC(=C(C=C3)Cl)Cl
Isomeric SMILES:C1CNC(=O)[C@@H]([C@H]1C2=CC=CC=C2)C3=CC(=C(C=C3)Cl)Cl

Technology Process of 2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans-

There total 6 articles about 2-Piperidinone, 3-(3,4-dichlorophenyl)-4-phenyl-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 132604-94-5
erythro-2-(3,4-dichlorophenyl)-4-cyano-3-phenylbutanoate d'ethyle

: 116731-95-4
trans-3-(3,4-dichlorophenyl)-4-phenylpiperidin-2-one

: 116731-95-4
cis-3-(3,4-dichlorophenyl)-4-phenylpiperidin-2-one

Guidance literature:: With hydrogen; acetic acid; platinum on activated charcoal; at 120 ℃; for 1.5h; under 105008 Torr; Yields of byproduct given;
DOI:10.1016/0223-5234(90)90129-Q

Reference yield: 60.0%

: 132604-94-5
erythro-2-(3,4-dichlorophenyl)-4-cyano-3-phenylbutanoate d'ethyle

: 116731-95-4
trans-3-(3,4-dichlorophenyl)-4-phenylpiperidin-2-one

: 116731-95-4
cis-3-(3,4-dichlorophenyl)-4-phenylpiperidin-2-one

Guidance literature:: With hydrogen; acetic acid; platinum on activated charcoal; at 120 ℃; for 1.5h; under 105008 Torr; Yields of byproduct given;
DOI:10.1016/0223-5234(90)90129-Q

Reference yield:

: 4360-47-8
cinnamonitrile

: 116731-95-4
trans-3-(3,4-dichlorophenyl)-4-phenylpiperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 45.5 percent / NaNH₂ / diethyl ether / 3 h / 5 - 10 °C

2: 60 percent / H₂, AcOH / 5percent Pt/C / 1.5 h / 120 °C / 105008 Torr

With hydrogen; sodium amide; acetic acid; platinum on activated charcoal; In diethyl ether;
DOI:10.1016/0223-5234(90)90129-Q