3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol

Base Information

Chemical Name:3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol
CAS No.:55697-81-9
Molecular Formula:C₁₆H₁₄N₂O
Molecular Weight:250.3
Hs Code.:
DSSTox Substance ID:DTXSID70514720
Wikidata:Q82375223

Synonyms:3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol;55697-81-9;SCHEMBL14495717;DTXSID70514720

Suppliers and Price of 3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:250.110613074
Heavy Atom Count:19
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=C1O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol

There total 7 articles about 3-Methyl-1,5-diphenyl-1H-pyrazol-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 1074-12-0
phenylglyoxal hydrate

: 20488-38-4
acetaldehyde phenylhydrazone

: 55697-81-9
4-hydroxy-3-methyl-1,5-diphenylpyrazole

: 95884-33-6
3-benzoyl-4-hydroxy-1,5-diphenylpyrazole

Guidance literature:: With magnesium sulfate; In acetic acid butyl ester; acetic acid; 20 deg C, 10 min, 110 deg C, 1 h;

Reference yield:

: 2-(3-Methyl-1,5-diphenyl-1H-pyrazol-4-yl)-prop-2-yl-hydroperoxide

: 55697-81-9
4-hydroxy-3-methyl-1,5-diphenylpyrazole

Guidance literature:: With sulfuric acid; In dichloromethane; for 12h;
DOI:10.1055/s-1983-30615

Reference yield:

: 3-methyl-1,5-diphenyl-4-(prop-1-en-2-yl)-1H-pyrazole

: 55697-81-9
4-hydroxy-3-methyl-1,5-diphenylpyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 30percent hydrogen peroxide, conc. sulfuric acid / CH₂Cl₂ / 4 h / Ambient temperature

2: 70percent aq. sulfuric acid / CH₂Cl₂ / 12 h

With sulfuric acid; dihydrogen peroxide; In dichloromethane;
DOI:10.1055/s-1983-30615