7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one

Base Information

Chemical Name:7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one
CAS No.:55727-53-2
Molecular Formula:C11H11N3O
Molecular Weight:201.228
Hs Code.:
European Community (EC) Number:867-784-1
ChEMBL ID:CHEMBL1570813
DSSTox Substance ID:DTXSID80408666
Nikkaji Number:J2.411.769C
Wikidata:Q82214216

Synonyms:55727-53-2;7-AMINO-1H,2H,3H,9H-PYRROLO[2,1-B]QUINAZOLIN-9-ONE;7-amino-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one;7-amino-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one;MLS000116101;CHEMBL1570813;DTXSID80408666;HMS2251J20;AKOS000149400;SMR000093085;CS-0226654;EN300-36528;D85506;MLS-0062008.0001;SR-01000092327;SR-01000092327-1;6-amino-2,3-trimethylene-3,4-dihydro-4-quinazolone;F2113-0311;Z316121144

Suppliers and Price of 7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-amino-1H,2H,3H,9H-pyrrolo[2,1-b]quinazolin-9-one
50mg
$ 90.00

American Custom Chemicals Corporation
7-AMINO-2,3-DIHYDROPYRROLO[2,1-B]QUINAZOLIN-9(1H)-ONE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
7-AMINO-2,3-DIHYDROPYRROLO[2,1-B]QUINAZOLIN-9(1H)-ONE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
7-AMINO-2,3-DIHYDROPYRROLO[2,1-B]QUINAZOLIN-9(1H)-ONE 95.00%
1G
$ 852.55

AK Scientific
7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one
10g
$ 1836.00

AK Scientific
7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one
250mg
$ 248.00

Total 3 raw suppliers

Chemical Property of 7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one

Chemical Property:

PSA：60.91000
LogP:1.50610
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:201.090211983
Heavy Atom Count:15
Complexity:326

Purity/Quality:

99% ^*data from raw suppliers

7-amino-1H,2H,3H,9H-pyrrolo[2,1-b]quinazolin-9-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=NC3=C(C=C(C=C3)N)C(=O)N2C1

Technology Process of 7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one

There total 7 articles about 7-Amino-1H,2H,3H,9H-pyrrolo[2,1-B]quinazolin-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1246451-95-5
6-N-(4'-nitrobenzylidene)aminodeoxyvasicinone

: 555-16-8
4-nitrobenzaldehdye

: 55727-53-2
7-amino-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one

Guidance literature:: In ethanol; at 80 ℃; for 1.5h;
DOI:10.1007/s10600-010-9583-8

Reference yield: 96.0%

: 55727-51-0
2-nitro-7,8-dihydro-6H,11H-pyrrolo-[2,1-b]quinazolin-11-one

: 55727-53-2
7-amino-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In ethanol; water; Cooling with ice; Heating;
DOI:10.1007/s10600-010-9583-8

Reference yield:

: 530-53-0
deoxyvasicinone

: 55727-53-2
7-amino-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 71.6 percent / 60percent HNO₃, ccH₂SO₄ / 15 h / Ambient temperature

2: 74.3 percent / H₂ / Pd/C / ethanol / Ambient temperature

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol;
DOI:10.1248/cpb.28.916