Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-

Base Information

• Chemical Name: Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-
• CAS No.: 55877-35-5
• Molecular Formula: C22H16O3
• Molecular Weight: 328.36100
• DSSTox Substance ID: DTXSID00425052
• Nikkaji Number: J1.761.492D
• Mol file: 55877-35-5.mol

Synonyms:55877-35-5;CBiol_000962;Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-;SCHEMBL11673920;DTXSID00425052;GDBOCNHOGRNDJM-UHFFFAOYSA-N;ICCB4_000258;2-Phenyl-3-(4-methoxybenzoyl)benzofuran;3-(4-methoxybenzoyl)-2-phenylbenzofuran;2-phenyl-3-(4'-methoxybenzoyl)benzofuran;(4-Methoxyphenyl)(2-phenyl-3-benzofuranyl)methanone

Chemical Property of Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-

Chemical Property:

• Melting Point: 70 °C(Solv: hexane (110-54-3))
• Boiling Point: 532.2±45.0 °C(Predicted)
• PSA: 39.44000
• Density: 1.199±0.06 g/cm3(Predicted)
• LogP: 5.33940
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 328.109944368
• Heavy Atom Count: 25
• Complexity: 448

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)C2=C(OC3=CC=CC=C32)C4=CC=CC=C4

Technology Process of Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-

There total 10 articles about Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-(2-((4-methoxyphenyl)ethynyl)phenoxy)-2-phenylacetic acid → 2-phenyl-3-(4'-methoxybenzoyl)benzofuran (55877-35-5)

Guidance literature:

With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 48h; Irradiation;

DOI:10.1039/c7cc04813k

Reference yield: 40.0%

carbon monoxide (201230-82-2) + para-iodoanisole (696-62-8) + 2-phenylethynylphenol (92151-73-0) → 2-phenyl-3-(4'-methoxybenzoyl)benzofuran (55877-35-5) + 4-methoxy-benzoic acid 2-phenylethynyl-phenyl ester

Guidance literature:

para-iodoanisole; With [2,2]bipyridinyl; Pd₂(dpa)3; In benzene; at 50 ℃; for 3h;

carbon monoxide; 2-phenylethynylphenol; With potassium carbonate; In acetonitrile; benzene; at 50 ℃; for 12h; Further stages.;

DOI:10.1021/jo010839c

Reference yield: 25.0%

2-(p-Methoxy)phenyl-3-benzoylbenzofuran (57664-47-8) → 2-phenyl-3-(4'-methoxybenzoyl)benzofuran (55877-35-5)

Guidance literature:

With hydrogenchloride; acetic acid; for 10h; Heating;

upstream raw materials:

2-(p-Methoxy)phenyl-3-benzoylbenzofuran

carbon monoxide

para-iodoanisole

2-phenylethynylphenol

Downstream raw materials:

2-phenyl-3-(4'-hydroxybenzoyl)benzofuran

2-Phenyl-3-(p-pyrrolidinoethoxybenzoyl)benzofuran

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 55877-35-5 (4-METHOXYPHENYL)(2-PHENYL-3-BENZOFURANYL)METHANONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send