Methyl(2-methyl-1-phenylpropyl)amine

Base Information

• Chemical Name: Methyl(2-methyl-1-phenylpropyl)amine
• CAS No.: 56129-56-7
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.263
• European Community (EC) Number: 874-332-7
• DSSTox Substance ID: DTXSID701256211
• Nikkaji Number: J544.965K
• Mol file: 56129-56-7.mol

Synonyms:methyl(2-methyl-1-phenylpropyl)amine;56129-56-7;N,2-dimethyl-1-phenylpropan-1-amine;SCHEMBL10435223;DTXSID701256211;AKOS005302759;CS-0260687;EN300-75603;G35299;Z164151714

Chemical Property of Methyl(2-methyl-1-phenylpropyl)amine

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 163.136099547
• Heavy Atom Count: 12
• Complexity: 114

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C(C1=CC=CC=C1)NC

Technology Process of Methyl(2-methyl-1-phenylpropyl)amine

There total 8 articles about Methyl(2-methyl-1-phenylpropyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isopropylmagnesium bromide (920-39-8) + N-Benzylidenemethylamine (622-29-7) → N-methyl-α-isopropylbenzylamine (56129-56-7)

Guidance literature:

With diethyl ether;

DOI:10.1021/ja01191a099

Reference yield:

Toluene-4-sulfonic acid (2R,3S)-3-methoxycarbonylamino-2-methyl-3-phenyl-propyl ester → N-methyl-α-isopropylbenzylamine (56129-56-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Ambient temperature;

DOI:10.1016/S0040-4020(01)81001-2

Reference yield:

trans-2-methyl-3-phenyl-3-(methoxycarbonylamino)propanol → N-methyl-α-isopropylbenzylamine (56129-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 254 mg / pyridine / CH₂Cl₂ / 4 h / 0 °C

2: 58.2 mg / LiAlH₄ / tetrahydrofuran / Ambient temperature

With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4020(01)81001-2

upstream raw materials:

isopropylmagnesium bromide

N-Benzylidenemethylamine

N-<2-Methyl-1-phenylpropyl>formamide

methyl α-<α-(methoxycarbonylamino)benzyl>propionate