Benzenepropanamide, N-(1-methylethyl)-

Base Information

• Chemical Name: Benzenepropanamide, N-(1-methylethyl)-
• CAS No.: 56146-87-3
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol file: 56146-87-3.mol

Synonyms:N-isopropylbenzenepropanamide;N-isopropyl-3-phenylpropanamidate;N-isopropyl-3-phenylpropionamide;N-Isopropyl-3-phenylpropanamide;

Chemical Property of Benzenepropanamide, N-(1-methylethyl)-

Chemical Property:

• PSA: 32.59000
• LogP: 2.98410

Purity/Quality:

99% ^*data from raw suppliers

N-Isopropyl-3-phenylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanamide, N-(1-methylethyl)-

There total 11 articles about Benzenepropanamide, N-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Nitro-1-phenyl-hexan-3-one (87377-86-4) + isopropylamine (75-31-0) → N-isopropyl-3-phenylpropanamidate (56146-87-3)

Guidance literature:

at 20 ℃; for 15h;

DOI:10.1016/S0040-4020(03)00022-X

Reference yield: 98.0%

phenethylmagnesium chloride (90878-19-6) + Isopropyl isocyanate (1795-48-8) → N-isopropyl-3-phenylpropanamidate (56146-87-3)

Guidance literature:

With copper(ll) bromide; In tetrahydrofuran; at 20 ℃; for 0.00294444h; Inert atmosphere; Flow reactor;

DOI:10.1002/anie.201807393

Reference yield: 92.0%

isopropylamine (75-31-0) + hydrocinnamic acid chloride (645-45-4) → N-isopropyl-3-phenylpropanamidate (56146-87-3)

Guidance literature:

With triethylamine; In diethyl ether;

DOI:10.1021/jo070591c

upstream raw materials:

methanol

[2-Chloro-1-methyl-2-phenyl-eth-(E)-ylidene]-isopropyl-amine

sodium methylate

N-Isopropyl-N-methyl-3-phenyl-propionamide

Downstream raw materials:

N-isopropyl-3-phenylbutanamide

N-isopropyl-3-phenylpropan-1-amine

3-phenylpropionamide

3-Phenyl-1-propanol