4-Formyl-2-(quinolin-8-yl)benzonitrile

Base Information

Chemical Name:4-Formyl-2-(quinolin-8-yl)benzonitrile
CAS No.:565203-62-5
Molecular Formula:C17H10N2O
Molecular Weight:258.279
Hs Code.:
DSSTox Substance ID:DTXSID00580019
Nikkaji Number:J2.389.780F
Wikidata:Q82470743

Synonyms:565203-62-5;4-Formyl-2-(quinolin-8-yl)benzonitrile;SCHEMBL6988176;DTXSID00580019

Suppliers and Price of 4-Formyl-2-(quinolin-8-yl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Formyl-2-(quinolin-8-yl)benzonitrile

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:258.079312947
Heavy Atom Count:20
Complexity:399

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)C3=C(C=CC(=C3)C=O)C#N)N=CC=C2

Technology Process of 4-Formyl-2-(quinolin-8-yl)benzonitrile

There total 5 articles about 4-Formyl-2-(quinolin-8-yl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 918413-80-6
(2-CYANO-5-FORMYLPHENYL)BORONIC ACID

: 108530-08-1
quinolin-8-yl trifluoromethanesulfonate

: 565203-62-5
4-formyl-2-(8-quinolinyl)benzonitrile

Guidance literature:: With palladium diacetate; potassium fluoride; CyJohnPhos; In methanol; toluene; at 68 ℃;
DOI:10.1016/j.tetlet.2006.10.008

Reference yield:

: 86-58-8
8-quinolinylboronic acid

: 565203-62-5
4-formyl-2-(8-quinolinyl)benzonitrile

Guidance literature:

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 565203-62-5
4-formyl-2-(8-quinolinyl)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / pyridine / -5 °C

2: 90 percent / KF; Pd(OAc)2; biphenyl-2-dicyclohexyl-phosphane / toluene; methanol / 68 °C

With pyridine; palladium diacetate; potassium fluoride; CyJohnPhos; In methanol; toluene;
DOI:10.1016/j.tetlet.2006.10.008