5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Base Information

Chemical Name:5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
CAS No.:56595-23-4
Molecular Formula:C16H12O6
Molecular Weight:300.26300
Hs Code.:
Mol file:56595-23-4.mol

Synonyms:Isocutellarein 7-methyl ether;5,8,4'-trihydroxy-7-methoxyflavone;7-methoxy-5,8,4'-trihydroxyflavone;Tectorigenin;

Suppliers and Price of 5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Chemical Property:

PSA：100.13000
LogP:2.58540

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

There total 8 articles about 5,8-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 89456-35-9
8-Hydroxy-2-(4-hydroxy-phenyl)-5,7-dimethoxy-chromen-4-one

: 56595-23-4
5,8,4'-trihydroxy-7-methoxyflavone

Guidance literature:: With aluminium trichloride; In acetonitrile; at 70 ℃; for 10h;
DOI:10.1246/bcsj.56.3773

Reference yield:

: 1486-50-6
4-(benzyloxy)benzoic acid chloride

: 56595-23-4
5,8,4'-trihydroxy-7-methoxyflavone

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 2 h / 120 °C

2: KOH, pyridine / 4 h / 60 °C

3: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C

4: 97 percent / H₂ / 10percent Pd/C / ethyl acetate; methanol

5: 98 percent / AlCl₃ / acetonitrile / 10 h / 70 °C

With pyridine; potassium hydroxide; aluminium trichloride; hydrogen; sodium acetate; palladium on activated charcoal; In methanol; acetic acid; ethyl acetate; acetonitrile;
DOI:10.1246/bcsj.56.3773

Reference yield:

: 54299-57-9
3-benzyloxy-2-hydroxy-4,6-dimethoxyacetophenone

: 56595-23-4
5,8,4'-trihydroxy-7-methoxyflavone

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 2 h / 120 °C

2: KOH, pyridine / 4 h / 60 °C

3: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C

4: 97 percent / H₂ / 10percent Pd/C / ethyl acetate; methanol

5: 98 percent / AlCl₃ / acetonitrile / 10 h / 70 °C

With pyridine; potassium hydroxide; aluminium trichloride; hydrogen; sodium acetate; palladium on activated charcoal; In methanol; acetic acid; ethyl acetate; acetonitrile;
DOI:10.1246/bcsj.56.3773