4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

Base Information

Chemical Name:4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-
CAS No.:56708-28-2
Molecular Formula:C13H8ClN3OS
Molecular Weight:289.74000
Hs Code.:
DSSTox Substance ID:DTXSID90401623
Wikidata:Q82204827

Synonyms:56708-28-2;4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-;SCHEMBL7099755;DTXSID90401623;ARCRSKORASYYDV-UHFFFAOYSA-N;AKOS005695055;2-(4-chloroanilino)-4H-pyrido[3,2-e]-1,3-thiazin-4-one

Suppliers and Price of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

Chemical Property:

PSA：86.61000
LogP:3.28270
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:289.0076608
Heavy Atom Count:19
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N=C1)SC(=NC2=O)NC3=CC=C(C=C3)Cl

Technology Process of 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

There total 6 articles about 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.1%

: 1417441-30-5
N-4-chlorophenyl-N'-nicotinoyl thiourea

: 56708-28-2
2-(4-chlorophenyl)amino-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:: In ethanol; for 0.5h; Reflux;

Reference yield:

: 1-(2-chloronicotinoyl)-3-(4-chlorophenyl)thiourea

: 56708-28-2
2-(4-chlorophenyl)amino-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:

Reference yield:

: 2942-59-8
2-chloronicotinic acid

: 56708-28-2
2-(4-chlorophenyl)amino-4H-pyrido[3,2-e][1,3]thiazin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 4 h / Reflux

2: acetone / 0.5 h / 20 °C

3: acetone / 4 h / 20 °C

4: ethanol / 0.5 h / Reflux

With thionyl chloride; In ethanol; acetone;