1-methyl-1H-indole-2-carbohydrazide

Base Information

Chemical Name:1-methyl-1H-indole-2-carbohydrazide
CAS No.:56809-86-0
Molecular Formula:C10H11N3O
Molecular Weight:189.217
Hs Code.:2933998090
DSSTox Substance ID:DTXSID40361122
Wikidata:Q82143269

Synonyms:1-methyl-1H-indole-2-carbohydrazide;56809-86-0;1-methylindole-2-carbohydrazide;1H-Indole-2-carboxylic acid, 1-methyl-, hydrazide;DTXSID40361122;MFCD00463397;STK039586;AKOS005382797;AS-8270;1-methylindole-2-carboxylic acid hydrazide;CS-0315823;AG-670/33304019

Suppliers and Price of 1-methyl-1H-indole-2-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Apolloscientific
1-Methyl-1H-indole-2-carbohydrazide
100mg
$ 174.00

American Custom Chemicals Corporation
1-METHYL-1H-INDOLE-2-CARBOHYDRAZIDE 95.00%
5MG
$ 502.01

Acints
1-Methyl-1H-indole-2-carboxylicacidhydrazide 95%+
5g
$ 1007.75

Acints
1-Methyl-1H-indole-2-carboxylicacidhydrazide 95%+
1g
$ 355.25

Acints
1-Methyl-1H-indole-2-carboxylicacidhydrazide 95%+
500mg
$ 210.25

Total 6 raw suppliers

Chemical Property of 1-methyl-1H-indole-2-carbohydrazide

Chemical Property:

PSA：63.54000
LogP:2.05690
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:189.090211983
Heavy Atom Count:14
Complexity:231

Purity/Quality:

99%, ^*data from raw suppliers

1-Methyl-1H-indole-2-carbohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C=C1C(=O)NN

Technology Process of 1-methyl-1H-indole-2-carbohydrazide

There total 7 articles about 1-methyl-1H-indole-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

: 18450-24-3
ethyl N-methylindole-2-carboxylate

: 56809-86-0
1-methyl-1H-indole-2-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 80 ℃; for 0.75h;
DOI:10.1016/j.ejmech.2013.08.018

Reference yield:

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 56809-86-0
1-methyl-1H-indole-2-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

1.2: 1 h / 20 °C

2.1: hydrazine hydrate / ethanol / 6 h / Reflux

With sodium hydride; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;
DOI:10.3906/kim-1202-62

Reference yield:

: 62-53-3
aniline

: 56809-86-0
1-methyl-1H-indole-2-carbohydrazide

Guidance literature:: Multi-step reaction with 5 steps

1: hydrogenchloride; sodium nitrite; tin(ll) chloride / -5 - 20 °C

2: acetic acid / ethanol / 1 h / 80 °C

3: polyphosphoric acid / toluene / 5 h / 100 °C

4: sodium hydride / tetrahydrofuran / 0.67 h / 0 °C

5: hydrazine hydrate / ethanol / 0.75 h / 80 °C

With hydrogenchloride; sodium hydride; hydrazine hydrate; acetic acid; tin(ll) chloride; sodium nitrite; In tetrahydrofuran; ethanol; toluene;
DOI:10.1016/j.ejmech.2013.08.018