1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Base Information

Chemical Name:1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
CAS No.:18450-24-3
Molecular Formula:C12H13 N O2
Molecular Weight:203.241
Hs Code.:2933990090
Mol file:18450-24-3.mol

Synonyms:Indole-2-carboxylicacid, 1-methyl-, ethyl ester (6CI,8CI); 2-(Ethoxycarbonyl)-N-methylindole;Ethyl 1-methyl-1H-indole-2-carboxylate; Ethyl 1-methylindole-2-carboxylate; NSC134575

Suppliers and Price of 1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Ethoxycarbonyl)-N-methylindole
25g
$ 1320.00

J&W Pharmlab
Ethyl1-methyl-indole-2-carboxylate 96%
1g
$ 398.00

Crysdot
Ethyl1-methyl-1H-indole-2-carboxylate 95+%
25g
$ 1191.00

Chemenu
Ethyl1-methyl-1H-indole-2-carboxylate 95%
25g
$ 1122.00

American Custom Chemicals Corporation
1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 95.00%
5G
$ 1135.13

AccelPharmtech
1H-Indole-2-carboxylicacid1-methylethylester 97.00%
25G
$ 9110.00

AccelPharmtech
1H-Indole-2-carboxylicacid1-methylethylester 97.00%
5G
$ 4850.00

Total 13 raw suppliers

Chemical Property of 1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

Vapor Pressure:0.000136mmHg at 25°C
Boiling Point:333.5°Cat760mmHg
Flash Point:155.5°C
PSA：31.23000
Density:1.11g/cm³
LogP:2.35500

Purity/Quality:

97% ^*data from raw suppliers

2-(Ethoxycarbonyl)-N-methylindole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-(Ethoxycarbonyl)-N-methylindole has been used as a reactant for the preparation of indole based small molecules as anticancer agents through SIRT1 inhibition.

Technology Process of 1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

There total 17 articles about 1-METHYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 74-88-4
methyl iodide

: 18450-24-3
ethyl N-methylindole-2-carboxylate

Guidance literature:: 2-carbethoxyindole; With sodium hydride; In DMF (N,N-dimethyl-formamide); for 0.333333 - 0.416667h;

methyl iodide; In DMF (N,N-dimethyl-formamide); at 40 - 45 ℃; for 1h;

Reference yield: 98.0%

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 77-78-1
dimethyl sulfate

: 18450-24-3
ethyl N-methylindole-2-carboxylate

Guidance literature:: With potassium carbonate; In acetonitrile; at 90 ℃; for 6h;

Reference yield: 83.0%

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 18450-24-3
ethyl N-methylindole-2-carboxylate

Guidance literature:: 2-carbethoxyindole; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 1h; Inert atmosphere;

methy halide; at 0 - 20 ℃; for 24h;
DOI:10.1039/c3ob40264a