Benzeneethanol, a-pentyl-

Base Information

• Chemical Name: Benzeneethanol, a-pentyl-
• CAS No.: 57243-11-5
• Molecular Formula: C13H20O
• Molecular Weight: 192.301
• Mol file: 57243-11-5.mol

Synonyms:

Chemical Property of Benzeneethanol, a-pentyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneethanol, a-pentyl-

There total 15 articles about Benzeneethanol, a-pentyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,2-epoxy-3-phenylpropane (4436-24-2) + lithium tetrabutylaluminate (14263-32-2) → 1-phenyl-heptan-2-ol (57243-11-5)

Guidance literature:

In pentane; at 35 ℃; for 24h;

DOI:10.1016/0040-4020(80)88033-1

Reference yield: 91.0%

1-nitro-1-phenyl-heptan-2-ol → 1-phenyl-heptan-2-ol (57243-11-5)

Guidance literature:

With hydrogen; palladium dihydroxide; In ethanol; at 70 ℃; under 750.075 Torr;

DOI:10.1002/anie.200604263

Reference yield: 89.0%

2-pentyl-3-phenyloxirane → 1-phenyl-heptan-2-ol (57243-11-5)

Guidance literature:

With cobalt(II) bis[bis((trifluoromethyl)sulfonyl)amide]; hydrogen; zinc trifluoromethanesulfonate; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; In tetrahydrofuran; at 80 ℃; for 16h; under 30003 Torr; regioselective reaction; Autoclave;

DOI:10.1002/anie.202002844

upstream raw materials:

1,2-epoxy-3-phenylpropane

lithium tetrabutylaluminate

n-pentylmagnesium bromide

phenylacetaldehyde

Downstream raw materials:

5-phenyl-6-undecanone

1-Phenyl-2-heptanone

Refernces

• 1、 Beller, Matthias,Junge, Kathrin,Leischner, Thomas,Li, Wu,Liu, Weiping. "A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides". supporting information. p. 11321 - 11324. Retrieved 2020/05/16.
• 2、 Fessard, Thomas C.,Motoyoshi, Hajime,Carreira, Erick M.. "Pd-catalyzed cleavage of benzylic nitro bonds: New opportunities for asymmetric synthesis". . p. 2078 - 2081. Retrieved 2008/02/13.