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(2,3-Epoxypropyl)benzene, also known as 1,2-epoxy-3-phenylpropane or styrene oxide, is an organic compound with the chemical formula C9H10O. It is a colorless liquid with a pungent odor and is derived from the reaction of benzene with ethylene oxide. (2,3-EPOXYPROPYL)BENZENE is an epoxide, which means it contains a three-membered ring consisting of two carbon atoms and one oxygen atom. (2,3-Epoxypropyl)benzene is an important intermediate in the synthesis of various chemicals, including polymers and pharmaceuticals. It is also a known carcinogen and mutagen, posing significant health risks when inhaled or absorbed through the skin. Due to its hazardous nature, it is crucial to handle this chemical with proper safety measures and precautions.

4436-24-2

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4436-24-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4436-24-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,3 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4436-24:
(6*4)+(5*4)+(4*3)+(3*6)+(2*2)+(1*4)=82
82 % 10 = 2
So 4436-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O/c1-2-4-8(5-3-1)6-9-7-10-9/h1-5,9H,6-7H2

4436-24-2 Well-known Company Product Price

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  • Aldrich

  • (332070)  (2,3-Epoxypropyl)benzene  98%

  • 4436-24-2

  • 332070-5G

  • 1,215.63CNY

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4436-24-2Relevant academic research and scientific papers

Iron-Catalyzed Prins-Peterson Reaction for the Direct Synthesis of δ4-2,7-Disubstituted Oxepenes

Sinka, Victoria,Padrón, Juan I.,Cruz, Daniel A.,Martín, Víctor S.

, p. 12632 - 12647 (2018)

A direct iron(III)-catalyzed Prins-Peterson reaction involving α-substituted γ-triphenylsilyl bis-homoallylic alcohols and aldehydes is described. Thus, cis-4-2,7-disubstituted oxepenes were synthesized in a diastereoselective reaction using su

Catalytic oxygen atom transfer promoted by tethered Mo(VI) dioxido complexes onto silica-coated magnetic nanoparticles

Colaiezzi, Roberta,Crucianelli, Marcello,Di Giuseppe, Andrea,Ferella, Francesco,Lazzarini, Andrea,Paolucci, Valentina

, (2021/11/30)

The preparation of three novel active and stable magnetic nanocatalysts for the selective liquid-phase oxidation of several olefins, has been reported. The heterogeneous systems are based on the coordination of cis-MoO2 moiety onto three different SCMNP@Si-(L1-L3) magnetically active supports, functionalized with silylated acylpyrazolonate ligands L1, L2 and L3. Nanocatalysts thoroughly characterized by ATR-IR spectroscopy, TGA and ICP-MS analyses, showed excellent catalytic performances in the oxidation of conjugated or unconjugated olefins either in organic or in aqueous solvents. The good magnetic properties of these catalytic systems allow their easy recyclability, from the reaction mixture, and reuse over five runs without significant decrease in the activity, either in organic or water solvent, demonstrating their versatility and robustness.

Primary Alcohols via Nickel Pentacarboxycyclopentadienyl Diamide Catalyzed Hydrosilylation of Terminal Epoxides

Lambert, Tristan H.,Steiniger, Keri A.

supporting information, p. 8013 - 8017 (2021/10/25)

The efficient and regioselective hydrosilylation of epoxides co-catalyzed by a pentacarboxycyclopentadienyl (PCCP) diamide nickel complex and Lewis acid is reported. This method allows for the reductive opening of terminal, monosubstituted epoxides to form unbranched, primary alcohols. A range of substrates including both terminal and nonterminal epoxides are shown to work, and a mechanistic rationale is provided. This work represents the first use of a PCCP derivative as a ligand for transition-metal catalysis.

A new and efficient methodology for olefin epoxidation catalyzed by supported cobalt nanoparticles

Rossi-Fernández, Lucía,Dorn, Viviana,Radivoy, Gabriel

supporting information, p. 519 - 526 (2021/03/31)

A new heterogeneous catalytic system consisting of cobalt nanoparticles (CoNPs) supported on MgO and tert-butyl hydroperoxide (TBHP) as oxidant is presented. This CoNPs@MgO/t-BuOOH catalytic combination allowed the epoxidation of a variety of olefins with good to excellent yield and high selectivity. The catalyst preparation is simple and straightforward from commercially available starting materials and it could be recovered and reused maintaining its unaltered high activity.

Direct synthesis of benzoxazinones via Cp*Co(III)-catalyzed C–H activation and annulation of sulfoxonium ylides with dioxazolones

Yu, Yongqi,Xia, Zhen,Wu, Qianlong,Liu, Da,Yu, Lin,Xiao, Yuanjiu,Tan, Ze,Deng, Wei,Zhu, Gangguo

supporting information, p. 1263 - 1266 (2020/10/08)

A highly novel and direct synthesis of benzoxazinones was developed via Cp*Co(III)-catalyzed C–H activation and [3 + 3] annulation between sulfoxonium ylides and dioxazolones. The reaction is conducted under base-free conditions and tolerates various functional groups. Starting from diverse readily available sulfoxonium ylides and dioxazolones, a variety of benzoxazinones could be synthesized in one step in 32%-75% yields.

Dendrimer crown-ether tethered multi-wall carbon nanotubes support methyltrioxorhenium in the selective oxidation of olefins to epoxides

Bizzarri, Bruno Mattia,Botta, Lorenzo,Crucianelli, Marcello,Fanelli, Angelica,Ferella, Francesco,Gontrani, Lorenzo,Sadun, Claudia,Saladino, Raffaele

, p. 17185 - 17194 (2020/05/18)

Benzo-15-crown-5 ether supported on multi-wall carbon nanotubes (MWCNTs) by tethered poly(amidoamine) (PAMAM) dendrimers efficiently coordinated methyltrioxorhenium in the selective oxidation of olefins to epoxides. Environmentally friendly hydrogen peroxide was used as a primary oxidant. Up to first and second generation dendrimer aggregates were prepared by applying a divergent PAMAM methodology. FT-IR, XRD and ICP-MS analyses confirmed the effective coordination of methyltrioxorhenium by the benzo-15-crown-5 ether moiety after immobilization on MWCNTs. The novel catalysts converted olefins to the corresponding epoxides in high yield without the use of Lewis base additives, or anhydrous hydrogen peroxide, the catalyst being stable for more than six oxidative runs. In the absence of the PAMAM structure, the synthesis of diols largely prevailed.

Nickel-catalyzed deoxygenation of oxiranes: Conversion of epoxides to alkenes

Mori, Takamichi,Takeuchi, Yoshihito,Hojo, Makoto

supporting information, (2020/01/24)

Deoxygenation of epoxides takes place under the catalysis of nickel in the presence of diethylzinc as a deoxygenation agent to yield alkenes. Epoxides with a wide variety of substitution patterns are deoxygenated in this catalytic system to give terminal, 1,1-disubstituted, 1,2-disubstituted, trisubstituted, and tetrasubstituted alkenes in high yields. Reactions of 1,2-disubstituted epoxides we examined proceeded in an E-stereoselective manner. High compatibility with other functional groups through this transformation was also observed.

A highly efficient heterogeneous catalyst of bimetal-organic frameworks for the epoxidation of olefin with H2O2

Huang, Hong,Lv, Jing,Meng, Xiang-Guang,Wang, Fei,Wu, Yan-Yan,Yu, Wen-Wang

, (2020/05/29)

A series of bimetel organic framework MnxCu1?x-MOF were prepared. The MOFs was characterized and analyzed by powder X-ray diffraction (PXRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and transmissio

One-pot synthesis of oxazolidinones and five-membered cyclic carbonates from epoxides and chlorosulfonyl isocyanate: Theoretical evidence for an asynchronous concerted pathway

Demir, Esra,Sari, Ozlem,?etinkaya, Yasin,Atmaca, Ufuk,Erdem, Safiye Sa?,?elik, Murat

supporting information, p. 1805 - 1819 (2020/11/07)

The one-pot reaction of chlorosulfonyl isocyanate (CSI) with epoxides having phenyl, benzyl and fused cyclic alkyl groups in different solvents under mild reaction conditions without additives and catalysts was studied. Oxazolidinones and five-membered cyclic carbonates were obtained in ratios close to 1:1 in the cyclization reactions. The best yields of these compounds were obtained in dichloromethane (DCM). Together with 16 known compounds, two novel oxazolidinone derivatives and two novel cyclic carbonates were synthesized with an efficient and straightforward method. Compared to the existing methods, the synthetic approach presented here provides the following distinct advantageous: being a one-pot reaction with metal-free reagent, having shorter reaction times, good yields and a very simple purification method. Moreover, using the density functional theory (DFT) method at the M06-2X/6-31+G(d,p) level of theory the mechanism of the cycloaddition reactions has been elucidated. The further investigation of the potential energy surfaces associated with two possible channels leading to oxazolidinones and five-membered cyclic carbonates disclosed that the cycloaddition reaction proceeds via an asynchronous concerted mechanism in gas phase and in DCM.

Rh(III)-Catalyzed sequential: Ortho-C-H oxidative arylation/cyclization of sulfoxonium ylides with quinones toward 2-hydroxy-dibenzo [b,d] pyran-6-ones

Cheng, Jiang,Dong, Yaqun,Sun, Song,Yu, Jin-Tao

supporting information, p. 6688 - 6691 (2020/07/03)

A rhodium(iii)-catalyzed ortho-C-H functionalization of sulfoxonium ylides followed by intramolecular annulation reactions with quinones was described, where the carbonyl in sulfoxonium ylides served as a chelation group. This protocol leads to the effici

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