CYCLOPROPYL 2-PYRIDYL KETONE

Base Information

• Chemical Name: CYCLOPROPYL 2-PYRIDYL KETONE
• CAS No.: 57276-28-5
• Molecular Formula: C9H9NO
• Molecular Weight: 147.17400
• Hs Code.: 2933399990
• Mol file: 57276-28-5.mol

Synonyms:Methanone,cyclopropyl-2-pyridinyl;cyclopropyl-pyridin-2-yl-methanone;ZLD0403;cyclopropyl-2-pyridyl ketone;cyclopropyl pyridinyl-2-methanone;

Chemical Property of CYCLOPROPYL 2-PYRIDYL KETONE

Chemical Property:

• Vapor Pressure: 0.0276mmHg at 25°C
• Boiling Point: 246.1oC at 760 mmHg
• Flash Point: 109oC
• PSA: 29.96000
• Density: 1.191g/cm3
• LogP: 1.67430

Purity/Quality:

97% ^*data from raw suppliers

Cyclopropyl(2-pyridyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclopropyl(2-pyridyl)methanone is a useful reactant for the synthesis of dihydronaphthalenes and dihydroquinolines.

Technology Process of CYCLOPROPYL 2-PYRIDYL KETONE

There total 5 articles about CYCLOPROPYL 2-PYRIDYL KETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

cyclopropyl(pyridin-2-yl)methanol (95188-13-9) → cyclopropyl(pyridin-2-yl)methanone (57276-28-5)

Guidance literature:

With oxygen; sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 6h;

DOI:10.1016/j.tet.2011.03.052

Reference yield: 55.0%

2-bromo-pyridine (109-04-6) + cyclopropropanecarbonitrile (5500-21-0) → cyclopropyl(pyridin-2-yl)methanone (57276-28-5)

Guidance literature:

2-bromo-pyridine; With n-butyllithium; In diethyl ether; hexane; at -60 ℃; for 0.333333h;

cyclopropropanecarbonitrile; In diethyl ether; hexane; at -60 - 20 ℃;

With hydrogenchloride; In diethyl ether; hexane; at 20 ℃; for 0.25h;

DOI:10.1021/jm060232u

Reference yield: 5.5%

C-cyclopropyl-C-pyridin-2-yl-methyleneamine (20127-47-3) → cyclopropyl(pyridin-2-yl)methanone (57276-28-5) + 1-cyclopropyl-1-pentanone (14113-86-1)

Guidance literature:

With hydrogenchloride; for 0.5h; Yield given; Heating;

DOI:10.1016/S0040-4020(01)91269-4

upstream raw materials:

2-bromo-pyridine

C-cyclopropyl-C-pyridin-2-yl-methyleneamine

cyclopropropanecarbonitrile

cyclopropyl(pyridin-2-yl)methanol

Downstream raw materials:

Cyclopropyl-phenyl-[2]pyridyl-methanol

Cyclopropyl-(4-methoxy-phenyl)-[2]pyridyl-methanol

1-(pyridin-2-yl)butan-1-one

cyclopropyl(pyridin-2-yl)methanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 57276-28-5 CYCLOPROPYL 2-PYRIDYL KETONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send