2-Chloro-6-nitro-4-phenylquinazoline

Base Information

Chemical Name:2-Chloro-6-nitro-4-phenylquinazoline
CAS No.:57370-28-2
Molecular Formula:C14H8ClN3O2
Molecular Weight:285.68500
Hs Code.:
DSSTox Substance ID:DTXSID30364400
Wikidata:Q82148352
ChEMBL ID:CHEMBL1553074

Synonyms:2-chloro-6-nitro-4-phenylquinazoline;57370-28-2;2-Chloro-6-nitro-4-phenyl-quinazoline;MLS001197364;SMR000555332;CHEMBL1553074;SCHEMBL11706982;BDBM54840;cid_1559438;DTXSID30364400;STK862376;AKOS001628354;2-chloranyl-6-nitro-4-phenyl-quinazoline;SR-01000441929;SR-01000441929-1

Suppliers and Price of 2-Chloro-6-nitro-4-phenylquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 2-Chloro-6-nitro-4-phenylquinazoline

Chemical Property:

PSA：71.60000
LogP:4.38160
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:285.0305042
Heavy Atom Count:20
Complexity:357

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=NC3=C2C=C(C=C3)[N+](=O)[O-])Cl

Technology Process of 2-Chloro-6-nitro-4-phenylquinazoline

There total 2 articles about 2-Chloro-6-nitro-4-phenylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26313-36-0
6-nitro-4-phenyl-1H-quinazolin-2-one

: 57370-28-2
6-nitro-2-chloro-4-phenylquinazoline

Guidance literature:: With phosphorus pentachloride; trichlorophosphate; at 100 ℃; for 4h;
DOI:10.1016/j.bmcl.2016.02.011

Reference yield:

: 1775-95-7
2-amino-5-nitrobenzophenone

: 57370-28-2
6-nitro-2-chloro-4-phenylquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / 150 °C

2: trichlorophosphate; phosphorus pentachloride / 4 h / 100 °C

With phosphorus pentachloride; trichlorophosphate;
DOI:10.1016/j.bmcl.2016.02.011