1-(Furan-2-yl)propan-2-amine

Base Information

• Chemical Name: 1-(Furan-2-yl)propan-2-amine
• CAS No.: 57580-64-0
• Molecular Formula: C7H11NO
• Molecular Weight: 125.16800
• Hs Code.: 2932190090
• European Community (EC) Number: 804-158-9
• DSSTox Substance ID: DTXSID00378190
• ChEMBL ID: CHEMBL4562538
• Mol file: 57580-64-0.mol

Synonyms:1-(furan-2-yl)propan-2-amine;57580-64-0;1-(2-furyl)propan-2-amine;2-Furan-2-yl-1-methyl-ethylamine;a-Methyl-2-furanethanamine;1-(2-furyl)-2-propanamine;SCHEMBL2022682;CHEMBL4562538;DTXSID00378190;HMS1704C05;BBL030348;MFCD05240377;STK500263;AKOS000161244;AKOS016341382;SB61180;BB 0237302;CS-0247239;EN300-36102;2-furan-2-yl-1-methyl-ethylamine, AldrichCPR;F2189-0007;Z285143986

Chemical Property of 1-(Furan-2-yl)propan-2-amine

Chemical Property:

• Flash Point: 3 °C
• PSA: 39.16000
• LogP: 1.86960
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 125.084063974
• Heavy Atom Count: 9
• Complexity: 85

Purity/Quality:

98%min ^*data from raw suppliers

1-(2-furyl)propan-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,C,F
• Statements: 11-23/25-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

Useful:

• Canonical SMILES: CC(CC1=CC=CO1)N

Technology Process of 1-(Furan-2-yl)propan-2-amine

There total 6 articles about 1-(Furan-2-yl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.9%

→ 1-(2-furyl)-2-aminopropane (57580-64-0,83687-81-4,83687-84-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Reflux; Cooling with ice;

Reference yield:

(E)-2-(2-nitroprop-1-en-1-yl)furan (134538-48-0) → 1-(2-furyl)-2-aminopropane (57580-64-0,83687-81-4,83687-84-7)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/jo01116a016

Reference yield:

furfural (98-01-1) → 1-(2-furyl)-2-aminopropane (57580-64-0,83687-81-4,83687-84-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / n-butylamine; AcOH / 2 h / 80 °C

2: LiAlH₄ / diethyl ether / cooling

With lithium aluminium tetrahydride; acetic acid; N-butylamine; In diethyl ether;

DOI:10.1016/j.bmc.2005.04.045

upstream raw materials:

(E)-2-(2-nitroprop-1-en-1-yl)furan

1-[2]furyl-acetone oxime

furfural