3-Thiophenecarboxylic acid, 2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino) carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]-

Base Information

Chemical Name:3-Thiophenecarboxylic acid, 2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino) carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]-
CAS No.:577780-09-7
Molecular Formula:C29H34F2N4O6S
Molecular Weight:604.675
Hs Code.:

3-Thiophenecarboxylic acid,
2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino)
carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]-

Synonyms:

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Chemical Property of 3-Thiophenecarboxylic acid, 2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino) carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]-

Chemical Property:

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Technology Process of 3-Thiophenecarboxylic acid, 2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino) carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]-

There total 1 articles about 3-Thiophenecarboxylic acid, 2-[[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino]-5-[4-[[(ethylamino) carbonyl]amino]phenyl]-4-[[(2-methoxyethyl)methylamino]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 577780-08-6
2-[N-(2,6-difluorobenzyl)-N-ethoxycarbonyl]amino-4-[N-(2-methoxyethyl)-N-methylaminomethyl]-5-[4-(ethylaminocarbonyl)aminophenyl]thiophene-3-carboxylic acid ethyl ester

: 577780-09-7
2-[N-(2,6-difluorobenzyl)-N-ethoxycarbonyl]amino-4-[N-(2-methoxyethyl)-N-methylaminomethyl]-5-[4-(ethylaminocarbonyl)aminophenyl]thiophene-3-carboxylic acid

Guidance literature:: 2-[N-(2,6-difluorobenzyl)-N-ethoxycarbonyl]amino-4-[N-(2-methoxyethyl)-N-methylaminomethyl]-5-[4-(ethylaminocarbonyl)aminophenyl]thiophene-3-carboxylic acid ethyl ester; With sodium hydroxide; water; In ethanol; at 60 ℃; for 5h;

With hydrogenchloride; In ethanol; water;

Reference yield:

: 20265-38-7
3-amino-2-methoxypyridine

: 577780-09-7
2-[N-(2,6-difluorobenzyl)-N-ethoxycarbonyl]amino-4-[N-(2-methoxyethyl)-N-methylaminomethyl]-5-[4-(ethylaminocarbonyl)aminophenyl]thiophene-3-carboxylic acid

: C₃₅H₄₀F₂N₆O₆S

Guidance literature:: With diethyl cyanophosphonate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 13h;

Reference yield:

: 577780-09-7
2-[N-(2,6-difluorobenzyl)-N-ethoxycarbonyl]amino-4-[N-(2-methoxyethyl)-N-methylaminomethyl]-5-[4-(ethylaminocarbonyl)aminophenyl]thiophene-3-carboxylic acid

: 81709-36-6
2-(4-Aminophenyl)N,N-dimethylacetamide

: C₃₉H₄₆F₂N₆O₆S

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 24h;