N-(4-iodophenyl)cyclopropanecarboxamide

Base Information

• Chemical Name: N-(4-iodophenyl)cyclopropanecarboxamide
• CAS No.: 23779-17-1
• Molecular Formula: C₁₀H₁₀INO
• Molecular Weight: 287.1
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID40351285
• Nikkaji Number: J3.553.826G
• Wikidata: Q82127582
• Mol file: 23779-17-1.mol

Synonyms:N-(4-iodophenyl)cyclopropanecarboxamide;23779-17-1;MFCD01327898;C10H10INO;Oprea1_484094;DTXSID40351285;STK409501;AKOS000272948;CS-0044980;FT-0680163;7N-005;W18816;A878144;AK-968/11368850;SR-01000408208;J-523063;SR-01000408208-1;Z30316436;F3148-3143

Chemical Property of N-(4-iodophenyl)cyclopropanecarboxamide

Chemical Property:

• Vapor Pressure: 5.57E-07mmHg at 25°C
• Melting Point: 214-216°
• Boiling Point: 411.5°Cat760mmHg
• PKA: 14.14±0.70(Predicted)
• Flash Point: 202.6°C
• PSA: 29.10000
• Density: 1.865g/cm³
• LogP: 2.71270
• Storage Temp.: 2-8°C(protect from light)
• Sensitive.: Light Sensitive
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 286.98071
• Heavy Atom Count: 13
• Complexity: 195

Purity/Quality:

99% ^*data from raw suppliers

N-(4-Iodophenyl)cyclopropanecarboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1C(=O)NC2=CC=C(C=C2)I

Technology Process of N-(4-iodophenyl)cyclopropanecarboxamide

There total 1 articles about N-(4-iodophenyl)cyclopropanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopropanecarboxylic acid chloride (4023-34-1) + p-aminoiodobenzene (540-37-4) → Cyclopropan-4-iod-carboxanilid (23779-17-1)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1002/rcm.7717

Reference yield:

Cyclopropan-4-iod-carboxanilid (23779-17-1) → 1-(2-oxopyrrolidin-1-yl)-4-iodobenzene (7661-34-9)

Guidance literature:

With aluminum oxide; ammonium iodide; at 200 ℃; for 0.5h; Microwave irradiation;

DOI:10.1002/rcm.7717

upstream raw materials:

cyclopropanecarboxylic acid chloride

p-aminoiodobenzene

Downstream raw materials:

1-(2-oxopyrrolidin-1-yl)-4-iodobenzene

Refernces