Technology Process of Pyridine, 2-[2-(4-methylphenyl)ethenyl]-, (Z)-
There total 4 articles about Pyridine, 2-[2-(4-methylphenyl)ethenyl]-, (Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-methylbenzyltriphenylphosphonium bromide;
In
tetrahydrofuran; mineral oil;
at 0 ℃;
for 1h;
Inert atmosphere;
Alkaline conditions;
pyridine-2-carbaldehyde;
In
tetrahydrofuran; mineral oil;
at 0 - 20 ℃;
for 13h;
Inert atmosphere;
DOI:10.1039/c5cc10401g
- Guidance literature:
-
With
diphenyl hydrogen phosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate;
In
toluene;
at 25 ℃;
for 1h;
Irradiation;
DOI:10.1039/c5cc10401g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere
1.2: 13 h / 0 - 20 °C / Inert atmosphere
2.1: [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; diphenyl hydrogen phosphate / toluene / 1 h / 25 °C / Irradiation
With
diphenyl hydrogen phosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; sodium hydride;
In
tetrahydrofuran; toluene; mineral oil;
DOI:10.1039/c5cc10401g
