1,2,3,4-Tetrahydro-1-nitrosoquinoline

Base Information

• Chemical Name: 1,2,3,4-Tetrahydro-1-nitrosoquinoline
• CAS No.: 5825-44-5
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.191
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID80355823
• Nikkaji Number: J903.981C
• Mol file: 5825-44-5.mol

Synonyms:1-Nitroso-1,2,3,4-tetrahydroquinoline;5825-44-5;1-nitroso-3,4-dihydro-2H-quinoline;1,2,3,4-tetrahydro-1-nitrosoquinoline;nitrosotetrahydroquinoline;SCHEMBL1437753;DTXSID80355823;FAWGKYZUQAMFJR-UHFFFAOYSA-N;STL563274;AKOS030508637;1-nitro so-1,2,3,4-tetrahydroquinoline;CS-0231161;EN300-1072819

Chemical Property of 1,2,3,4-Tetrahydro-1-nitrosoquinoline

Chemical Property:

• PSA: 32.67000
• LogP: 2.18560
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 162.079312947
• Heavy Atom Count: 12
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

1-NITROSO-1,2,3,4-TETRAHYDROQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=CC=CC=C2N(C1)N=O

Technology Process of 1,2,3,4-Tetrahydro-1-nitrosoquinoline

There total 5 articles about 1,2,3,4-Tetrahydro-1-nitrosoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2,3,4-tetrahydroisoquinoline (635-46-1) → N-nitroso-1,2,3,4-tetrahydroquinoline (5825-44-5)

Guidance literature:

With sulfuric acid; sodium chloride; sodium nitrite; In dichloromethane;

Reference yield: 100.0%

1,2,3,4-tetrahydroisoquinoline (635-46-1) + isopentyl nitrite (110-46-3) → N-nitroso-1,2,3,4-tetrahydroquinoline (5825-44-5)

Guidance literature:

With 4-(1,1-dimethylethyl)benzoic acid; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1039/c9cc04529e

Reference yield: 94.0%

1,2,3,4-tetrahydroquinoline hydrochloride (2739-17-5) → N-nitroso-1,2,3,4-tetrahydroquinoline (5825-44-5)

Guidance literature:

With sodium nitrate; In water; acetic acid; for 2h; Ambient temperature;

upstream raw materials:

decahydroquinoline

1,2,3,4-tetrahydroisoquinoline

1,2,3,4-tetrahydroquinoline hydrochloride

isopentyl nitrite

Downstream raw materials:

1-amino-1,2,3,4-tetrahydroquinoline

1,2,3,4-tetrahydroisoquinoline

decahydroquinoline

1-(2-Aminoethyl)-5,6-dihydro-2-methyl-4H-pyrrolo<3.2.1-i,j>chinolin