4-Chloroquinolin-3-amine

Base Information

Chemical Name:4-Chloroquinolin-3-amine
CAS No.:58401-43-7
Molecular Formula:C9H7ClN2
Molecular Weight:178.61800
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90355793
Nikkaji Number:J89.979H
Wikidata:Q82134834
Mol file:58401-43-7.mol

Synonyms:4-chloroquinolin-3-amine;58401-43-7;3-AMINO-4-CHLOROQUINOLINE;4-Chloro-3-quinolinamine;MFCD00234511;3-Quinolinamine, 4-chloro-;SCHEMBL201997;DTXSID90355793;AMY19774;AKOS022640096;DS-8767;SB67806;SY041633;CS-0060572;FT-0723606;EN300-6475333;A869457

Suppliers and Price of 4-Chloroquinolin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloroquinolin-3-amine
100mg
$ 285.00

SynQuest Laboratories
4-Chloro-3-quinolinamine 95%
1 g
$ 208.00

SynQuest Laboratories
4-Chloro-3-quinolinamine 95%
5 g
$ 520.00

Crysdot
4-Chloroquinolin-3-amine 98%
10g
$ 320.00

Crysdot
4-Chloroquinolin-3-amine 98%
25g
$ 630.00

Crysdot
4-Chloroquinolin-3-amine 98%
5g
$ 210.00

ChemScene
4-Chloroquinolin-3-amine
1g
$ 64.00

ChemScene
4-Chloroquinolin-3-amine
10g
$ 298.00

ChemScene
4-Chloroquinolin-3-amine
5g
$ 195.00

Chemenu
3-Amino-4-chloroquinoline 98%
5g
$ 196.00

Total 39 raw suppliers

Chemical Property of 4-Chloroquinolin-3-amine

Chemical Property:

Melting Point:142-143 °C
Boiling Point:308.1±22.0 °C(Predicted)
PKA:3.55±0.24(Predicted)
PSA：38.91000
Density:1.363±0.06 g/cm3(Predicted)
LogP:3.05160
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:178.0297759
Heavy Atom Count:12
Complexity:163

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloroquinolin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(C=N2)N)Cl

Technology Process of 4-Chloroquinolin-3-amine

There total 8 articles about 4-Chloroquinolin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 580-17-6
3-aminoquinoline

: 58401-43-7
3-amino-4-chloroquinoleine

Guidance literature:: With 1-chloro-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one; In N,N-dimethyl-formamide; at 20 ℃; for 12h; regioselective reaction;
DOI:10.1021/acs.orglett.6b00547

Reference yield:

: 39061-97-7
4-chloro-3-nitroquinoline

: 58401-43-7
3-amino-4-chloroquinoleine

Guidance literature:: With ethanol; nickel; Hydrogenation;
DOI:10.1021/ja01150a002

Reference yield:

: 50332-66-6
3-nitro-quinolin-4-ol

: 58401-43-7
3-amino-4-chloroquinoleine

Guidance literature:: Multi-step reaction with 2 steps

1: phosphoryl chloride

2: Raney nickel; ethanol / Hydrogenation

With ethanol; nickel; trichlorophosphate;
DOI:10.1021/ja01150a002