1-(4-Fluorophenyl)-2-methylprop-2-en-1-one

Base Information

• Chemical Name: 1-(4-Fluorophenyl)-2-methylprop-2-en-1-one
• CAS No.: 58472-45-0
• Molecular Formula: C10H9FO
• Molecular Weight: 164.179
• DSSTox Substance ID: DTXSID00534153
• Wikidata: Q82407815

Synonyms:58472-45-0;1-(4-Fluorophenyl)-2-methylprop-2-en-1-one;1-(4-Fluorophenyl)-2-methyl-2-propenone;4'-fluoro-2-methylacrylophenone;SCHEMBL11802097;DTXSID00534153;DUOJDZXDNXBCHN-UHFFFAOYSA-N;MFCD20921053;AKOS017741583;NCGC00161052-01;1-(4-Fluoro-phenyl)-2-methyl-propenone;SY312249

Chemical Property of 1-(4-Fluorophenyl)-2-methylprop-2-en-1-one

Chemical Property:

• Boiling Point: 40-42 °C(Press: 0.1 Torr)
• PSA: 17.07000
• Density: 1.072±0.06 g/cm3(Predicted)
• LogP: 2.58450
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 164.063743068
• Heavy Atom Count: 12
• Complexity: 190

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)C1=CC=C(C=C1)F

Technology Process of 1-(4-Fluorophenyl)-2-methylprop-2-en-1-one

There total 6 articles about 1-(4-Fluorophenyl)-2-methylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-(4-fluorophenyl)propan-1-one (456-03-1) + N,N-dimethyl acetamide (127-19-5,116057-81-9) → 1-(p-fluorophenyl)-2-methyl-2-propen-1-one (58472-45-0)

Guidance literature:

With dipotassium peroxodisulfate; iron(III) chloride hexahydrate; at 110 ℃; for 4h; Sealed tube;

DOI:10.1002/ejoc.201500189

Reference yield: 85.0%

→ 1-(p-fluorophenyl)-2-methyl-2-propen-1-one (58472-45-0)

Guidance literature:

With sodium tetrachloroaurate(III) dihyrate; In dimethyl sulfoxide; at 100 ℃; for 2h;

Reference yield: 65.0%

(1-(4-fluorophe nyl)-2-(triphenyl-λ5-phosphanylidene)propan-1-one) → 1-(p-fluorophenyl)-2-methyl-2-propen-1-one (58472-45-0)

Guidance literature:

With dmap; carbon dioxide; phenylsilane; In acetonitrile; for 30h; under 760.051 Torr;

upstream raw materials:

1-(4-fluorophenyl)propan-1-one

N,N-dimethyl acetamide

carbon dioxide

4-fluorobenzoyl chloride

Downstream raw materials:

5-(4-Fluoro-phenyl)-2,6-dimethyl-6,7-dihydro-[1,3,4]oxadiazepine

5-Fluoro-2-Methyl-Indan-1-One

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 58472-45-0 2-Propen-1-one, 1-(4-fluorophenyl)-2-methyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send