Piperidine, 1-(4-hydroxybenzoyl)-

Base Information

Chemical Name:Piperidine, 1-(4-hydroxybenzoyl)-
CAS No.:58547-68-5
Molecular Formula:C12H15NO2
Molecular Weight:205.257
Hs Code.:
Mol file:58547-68-5.mol

Synonyms:(4-hydroxy-phenyl)-piperidin-1-yl-methanone;4-(1-piperidinocarbonyl)phenol;1-(4-hydroxy-benzoyl)-piperidine;1-(4-hydroxybenzoyl)piperidine;1-(4-Hydroxy-benzoyl)-piperidin;

Suppliers and Price of Piperidine, 1-(4-hydroxybenzoyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-[(PIPERIDIN-1-YL)CARBONYL]PHENOL 95.00%
5MG
$ 504.92

aablocks
4-[(Piperidin-1-yl)carbonyl]phenol 96%
25g
$ 934.00

aablocks
4-[(Piperidin-1-yl)carbonyl]phenol 96%
10g
$ 467.00

aablocks
4-[(Piperidin-1-yl)carbonyl]phenol 96%
5g
$ 267.00

Total 3 raw suppliers

Chemical Property of Piperidine, 1-(4-hydroxybenzoyl)-

Chemical Property:

PSA：40.54000
LogP:1.95620

Purity/Quality:

98% ^*data from raw suppliers

4-[(PIPERIDIN-1-YL)CARBONYL]PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-[(Piperidin-1-yl)carbonyl]phenol is used as a reactant in the preparation of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.

Technology Process of Piperidine, 1-(4-hydroxybenzoyl)-

There total 14 articles about Piperidine, 1-(4-hydroxybenzoyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 110-89-4
piperidine

: 402-45-9
4-hydroxybenzotrifluoride

: 58547-68-5
(4-hydroxyphenyl)(piperidin-1-yl)methanone

Guidance literature:: With water; sodium hydroxide; In 1,4-dioxane; at 75 ℃; for 48h;
DOI:10.1021/ol100507n

Reference yield: 76.0%

: 2591-86-8
N-Formylpiperidine

: 99-96-7
4-hydroxy-benzoic acid

: 58547-68-5
(4-hydroxyphenyl)(piperidin-1-yl)methanone

Guidance literature:: With tert.-butylhydroperoxide; [Cu(1,3-bis(carboxymethyl)imidazole)₂]; In water; at 100 ℃; for 1.66667h;
DOI:10.1002/ejoc.201600991

Reference yield: 67.3%

: 110-89-4
piperidine

: 99-96-7
4-hydroxy-benzoic acid

: 58547-68-5
(4-hydroxyphenyl)(piperidin-1-yl)methanone

Guidance literature:: 4-hydroxy-benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 2.5h; Inert atmosphere;

piperidine; With triethylamine; In dichloromethane; for 0.5h; Inert atmosphere;