Chemical Property of N-Formylpiperidine
Chemical Property:
- Appearance/Colour:clear colourless to slightly yellow liquid
- Vapor Pressure:0.1 mm Hg ( 25 °C)
- Melting Point:-31 °C
- Refractive Index:n20/D 1.484(lit.)
- Boiling Point:222.5 °C at 760 mmHg
- PKA:-0.44±0.20(Predicted)
- Flash Point:91.7 °C
- PSA：20.31000
- Density:1.087 g/cm3
- LogP:1.20250
- Storage Temp.:Store below +30°C.
- Water Solubility.:freely soluble
- XLogP3:0
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:0
- Exact Mass:113.084063974
- Heavy Atom Count:8
- Complexity:76.6
- Purity/Quality:
-
99%, *data from raw suppliers
Formylpiperidine *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn; 
Xi
- Hazard Codes:Xn,Xi
- Statements:
21/22-36/37/38
- Safety Statements:
26-36/37-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1CCN(CC1)C=O
-
Description
This simple piperidine base has recently been discovered in the oxygenated
fraction from Piper nigrum. The structure has been elucidated from chemical
and spectroscopic data.
-
Uses
Solvent for polar and nonpolar compounds, as well as many high polymers; gas absorption; plastics modifiers. Reactant for: Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoateVilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychlorideCO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamidesSynthesis of alternating copolymers for organic photovoltaic applicationsOne-pot double functionalization of π-deficient heterocyclic lithium reagentsSynthesis of thermally stable piezofluorochromic aggregation-induced emission compounds
