(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid

Base Information

Chemical Name:(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid
CAS No.:58607-69-5
Molecular Formula:C18H20N2O3
Molecular Weight:312.368
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60423791
Nikkaji Number:J1.131.016H
Mol file:58607-69-5.mol

Synonyms:58607-69-5;(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid;H-D-PHE-D-PHE-OH;(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoic acid;D-Phe-D-Phe-OH;SCHEMBL5065345;DTXSID60423791;GKZIWHRNKRBEOH-HZPDHXFCSA-N;(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid;MFCD00237217;AKOS016843441;DS-3915;CS-0149839;A869398;(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid (H-D-Phe-D-Phe-OH)

Suppliers and Price of (R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95+%
25g
$ 304.00

Chemenu
D-phenylalanyl-D-phenylalanine 95%
10g
$ 131.00

Chemenu
D-phenylalanyl-D-phenylalanine 95%
25g
$ 287.00

American Custom Chemicals Corporation
H-D-PHE-D-PHE-OH 95.00%
1G
$ 684.00

American Custom Chemicals Corporation
H-D-PHE-D-PHE-OH 95.00%
5MG
$ 501.70

Ambeed
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95%
1g
$ 30.00

Ambeed
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95%
250mg
$ 12.00

Ambeed
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95%
5g
$ 82.00

Ambeed
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95%
10g
$ 147.00

Activate Scientific
(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid 95% ee
5 g
$ 128.00

Total 31 raw suppliers

Chemical Property of (R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid

Chemical Property:

Vapor Pressure:2.01E-14mmHg at 25°C
Melting Point:130-131 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling Point:582.8oC at 760 mmHg
PKA:3.41±0.10(Predicted)
Flash Point:306.2oC
PSA：92.42000
Density:1.229g/cm3
LogP:2.45970
Storage Temp.:-15°C
XLogP3:-0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:312.14739250
Heavy Atom Count:23
Complexity:388

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)O)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](C(=O)N[C@H](CC2=CC=CC=C2)C(=O)O)N

Technology Process of (R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid

There total 9 articles about (R)-2-((R)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2448-45-5
Cbz-D-Phe

: 58607-69-5
D-phenylalaninyl-D-phenylalanine

Guidance literature:: Reaktion ueber mehrere Stufen;

Reference yield:

: 86123-10-6
Fmoc-D-Phe-OH

: 58607-69-5
D-phenylalaninyl-D-phenylalanine

Guidance literature:: Fmoc-D-Phe-OH; With 2-chlorotrityl chloride polystyrene resin; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.5h; 2-chlorotrityl chloride resin

With piperidine; In N,N-dimethyl-formamide; for 0.5h; 2-chlorotrityl chloride resin

Fmoc-D-Phe-OH; Further stages;
DOI:10.1021/ja310019x

Reference yield:

: 47004-38-6
D-phenylalanine benzyl ester

: (D-F)3-OBn

: 58607-69-5
D-phenylalaninyl-D-phenylalanine

: D-Phe-D-Phe-OBn

: 1021171-64-1
(3R,6R)-3,6-dibenzylpiperazine-2,5-dione

Guidance literature:: With aminolysin-A; In water; dimethyl sulfoxide; at 50 ℃; for 6h; pH=8; aq. phosphate buffer; Enzymatic reaction;
DOI:10.1039/c0ob00403k