Z-D-Phe-OH

Base Information Edit

Chemical Name:Z-D-Phe-OH
CAS No.:2448-45-5
Molecular Formula:C17H17NO4
Molecular Weight:299.326
Hs Code.:29242990
DSSTox Substance ID:DTXSID901285286
Nikkaji Number:J208.193H
Wikidata:Q106902928
ChEMBL ID:CHEMBL63865
Mol file:2448-45-5.mol

Synonyms:Z-D-Phe-OH;2448-45-5;N-Cbz-D-phenylalanine;Z-D-phenylalanine;(2R)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoic acid;N-benzyloxycarbonyl-D-phenylalanine;((Benzyloxy)carbonyl)-D-phenylalanine;CHEMBL63865;D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-;N-(Benzyloxycarbonyl)-D-phenylalanine;Cbz-Phe-OH;Cbz-D-Phenylalanine;N-Carbobenzoxy-D-phenylalanine;N-(Carbobenzyloxy)-D-phenylalanine;benzyloxycarbonyl-D-phenylalanine;Cbz-D-Phe;MFCD00063151;Z-DPhe-OH;N-[(Phenylmethoxy)carbonyl]-D-phenylalanine;carbobenzoxy-d-phenylalanine;SCHEMBL219151;DTXSID901285286;BDBM50043798;AKOS015924112;AM82159;CS-W009960;HY-W009244;N-CARBOBENZYLOXY-D-PHENYLALANINE;1-N-(Benzyloxycarbonyl)-D-phenylalanine;Nalpha -benzyloxycarbonyl-D-phenylalanine;AC-24115;AS-12744;C0662;EN300-121304;F10792;1--N-(BENZYLOXYCARBONYL)-D-PHENYLALANINE;A817332;(R)-2-benzyloxycarbonylamino-3-phenylpropionic acid;J-300210;(R)-2-(benzyloxycarbonylamino)-3-phenylpropanoic acid;(R)-2-Benzyloxycarbonylamino-3-phenyl-propionic acid;(R)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanoic acid;N-alpha-BenZyloxycarbonyl-D-phenylalanine (CbZ-D-Phe-OH);(2R)-2-{[(BENZYLOXY)CARBONYL]AMINO}-3-PHENYLPROPANOIC ACID

Suppliers and Price of Z-D-Phe-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cbz-D-phenylalanine
5g
$ 210.00

TRC
N-Cbz-D-phenylalanine
1g
$ 120.00

TCI Chemical
N-Carbobenzoxy-D-phenylalanine >98.0%(T)
5g
$ 89.00

TCI Chemical
N-Carbobenzoxy-D-phenylalanine >98.0%(T)
1g
$ 32.00

Sigma-Aldrich
Z-D-Phe-OH
25g
$ 760.00

Iris Biotech GmbH
Z-D-Phe-OH
25 g
$ 243.00

Iris Biotech GmbH
Z-D-Phe-OH
100 g
$ 641.25

Iris Biotech GmbH
Z-D-Phe-OH
5 g
$ 74.25

Frontier Specialty Chemicals
N-Carbobenzyloxy-D-phenylalanine 98%
1g
$ 27.00

ChemPep
Z-D-Phe-OH ≥98%
25g
$ 221.00

Total 97 raw suppliers

Chemical Property of Z-D-Phe-OH Edit

Chemical Property:

Vapor Pressure:2.76E-11mmHg at 25°C
Melting Point:85-88 °C
Refractive Index:-5.3 ° (C=4, AcOH)
Boiling Point:511.5 °C at 760 mmHg
PKA:3.86±0.10(Predicted)
Flash Point:263.1 °C
PSA：75.63000
Density:1.248 g/cm³
LogP:2.99960
Storage Temp.:−20°C
Water Solubility.:Soluble in methanol. Slightly soluble in water.
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:299.11575802
Heavy Atom Count:22
Complexity:360

Purity/Quality:

99% ^*data from raw suppliers

N-Cbz-D-phenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](C(=O)O)NC(=O)OCC2=CC=CC=C2
Uses N-Cbz-D-phenylalanine is an N-Cbz-protected form of D-Phenylalanine (P319410). D-Phenylalanine is an essential amino acid that serves as a primary precursor for the biosynthesis of catecholamines in the body. D-Phenylalanine is also known to antagonize stress-induced analgesia in humans, and also acts as an anti-enkephalinase agent.

Technology Process of Z-D-Phe-OH

There total 53 articles about Z-D-Phe-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1417694-04-2
(R)-2-amino-3-(4-ethoxyphenyl)propionic acid hydrochloride

: 501-53-1,94274-21-2
benzyl chloroformate

: 2448-45-5
Cbz-D-Phe

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 0 - 20 ℃;

Reference yield: 85.0%

(R)-2-Benzyloxycarbonylamino-3-phenyl-propionic acid allyl ester: (R)-2-Benzyloxycarbonylamino-3-phenyl-propionic acid allyl ester

: 2448-45-5
Cbz-D-Phe

Guidance literature:: With polymethylhydrosiloxane; zinc(II) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0040-4020(01)00187-9