rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide

Base Information

Chemical Name:rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide
CAS No.:586414-93-9
Molecular Formula:C₂₃H₂₈ClN₃O₆S
Molecular Weight:510.011
Hs Code.:
Mol file:586414-93-9.mol

Synonyms:

Suppliers and Price of rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ractrans-2-HydroxyGlyburide
25mg
$ 1585.00

Medical Isotopes, Inc.
ractrans-2-HydroxyGlyburide
25 mg
$ 2440.00

Total 1 raw suppliers

Chemical Property of rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide

Chemical Property:

Purity/Quality:: ractrans-2-HydroxyGlyburide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses rac trans-2-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (MIV-metabolite).

Technology Process of rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide

There total 3 articles about rel-5-Chloro-N-[2-[4-[[[[[(1R,2R)-2-hydroxycyclohexyl]aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 14511-59-2
Ethyl 4-<2-(5-chloro-2-methoxybenzamido)ethyl>benzenesulfonamidecarbamate

: 931-16-8,6850-38-0,6982-39-4,33092-82-9,38898-70-3,74111-21-0,108267-20-5,931-15-7
(+/-)-trans-2-aminocyclohexanol

: 586414-93-9
1-{[4-[2-(5-chloro-2-methoxybenzamido)ethyl]phenyl]sulfonyl}-3-(trans-2-hydroxycyclohexyl)urea

Guidance literature:: In 1,4-dioxane; for 10h; Heating;
DOI:10.1016/S0968-0896(02)00606-5

Reference yield:

: 16673-34-0
5-chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide

: 586414-93-9
1-{[4-[2-(5-chloro-2-methoxybenzamido)ethyl]phenyl]sulfonyl}-3-(trans-2-hydroxycyclohexyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / K₂CO₃ / acetone / 26 h / Heating

2: 25 percent / dioxane / 10 h / Heating

With potassium carbonate; In 1,4-dioxane; acetone;
DOI:10.1016/S0968-0896(02)00606-5