14511-59-2Relevant articles and documents
Synthesis technology of glibenclamide
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Paragraph 0043; 0045, (2017/08/25)
The invention provides a novel synthesis technology of a glibenclamide bulk pharmaceuticals. The glibenclamide product is finally prepared by taking sulfamide as a starting raw material through the four steps of a secondary condensation reaction, a compounding reaction, a dealcoholization reaction and refining. The technology has the advantages of being high in yield, low in purity, easy and convenient to operate, suitable for industrialized production and the like.
SYNTHESIS OF 4-trans-BENZENESULFONYL>UREIDO>CYCLOHEXANOL HEMISUCCINATE ESTER
Stephon, Robert L.,Niedbala, R. Sam,Schray, Keith J.,Heindel, Ned D.
, p. 339 - 342 (2007/10/03)
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