Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)-

Base Information

Chemical Name:Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)-
CAS No.:586972-81-8
Molecular Formula:C21H32O6
Molecular Weight:380.481
Hs Code.:

Synonyms:

Suppliers and Price of Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)-

There total 3 articles about Butanedioic acid, 2-[3-(4-ethoxyphenyl)propyl]-3-hydroxy-, bis(1-methylethyl) ester, (2R,3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: diisopropyl (2R,3S)-2-[(2E)-3-(4-ethoxyphenyl)-2-propenyl]-3-hydroxybutanedioate

: 586972-81-8
2R-[3-(4-ethoxy-phenyl)-propyl]-3S-hydroxy-succinic acid diisopropylester

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 14h; under 1500.15 Torr;

Reference yield:

: 83541-68-8,6947-09-7
2S-Hydroxybutan-1,4-dioic acid diisopropyl ester

: 586972-81-8
2R-[3-(4-ethoxy-phenyl)-propyl]-3S-hydroxy-succinic acid diisopropylester

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -78 - -30 °C

1.2: -78 - 20 °C

2.1: triethylamine / palladium diacetate; tris-(o-tolyl)phosphine / acetonitrile / 2 h / Heating / reflux

3.1: hydrogen / palladium 10% on activated carbon / methanol / 16.5 h / 760.05 Torr

With hydrogen; triethylamine; lithium hexamethyldisilazane; palladium diacetate; palladium 10% on activated carbon; tris-(o-tolyl)phosphine; In tetrahydrofuran; methanol; acetonitrile;

Reference yield:

: 210711-58-3
(2R,3S)-diisopropyl 2-allyl-3-hydroxysuccinate

: 586972-81-8
2R-[3-(4-ethoxy-phenyl)-propyl]-3S-hydroxy-succinic acid diisopropylester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / palladium diacetate; tris-(o-tolyl)phosphine / acetonitrile / 2 h / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / methanol / 16.5 h / 760.05 Torr

With hydrogen; triethylamine; palladium diacetate; palladium 10% on activated carbon; tris-(o-tolyl)phosphine; In methanol; acetonitrile;