(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

Base Information

Chemical Name:(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid
CAS No.:586972-83-0
Molecular Formula:C₁₈H₂₄O₆
Molecular Weight:336.385
Hs Code.:

Synonyms:(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

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Chemical Property of (2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

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Technology Process of (2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

There total 3 articles about (2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 586972-82-9
(2R,3S)-2-[3-(4-ethoxyphenyl)propyl]-3-hydroxybutanedioic acid

: 77-76-9
2,2-dimethoxy-propane

: 67-64-1
acetone

: 586972-83-0
(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

Guidance literature:: With copper dichloride; at 20 ℃; for 14h;

Reference yield:

: diisopropyl (2R,3S)-2-[(2E)-3-(4-ethoxyphenyl)-2-propenyl]-3-hydroxybutanedioate

: 586972-83-0
(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium 10% on activated carbon / methanol / 16.5 h / 760.05 Torr

2.1: sodium hydroxide / tetrahydrofuran; water / 16 h / 20 °C

2.2: pH 3

3.1: copper dichloride / acetone / 16 h / 20 °C

With sodium hydroxide; hydrogen; copper dichloride; palladium 10% on activated carbon; In tetrahydrofuran; methanol; water; acetone;

Reference yield:

: 586972-81-8
2R-[3-(4-ethoxy-phenyl)-propyl]-3S-hydroxy-succinic acid diisopropylester

: 586972-83-0
(2R)-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(4-ethoxyphenyl)pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 16 h / 20 °C

1.2: pH 3

2.1: copper dichloride / acetone / 16 h / 20 °C

With sodium hydroxide; copper dichloride; In tetrahydrofuran; water; acetone;