4-FLUORODIPHENYLMETHANE

Base Information

• Chemical Name: 4-FLUORODIPHENYLMETHANE
• CAS No.: 587-79-1
• Molecular Formula: C13H11F
• Molecular Weight: 186.229
• Hs Code.: 2903999090
• Mol file: 587-79-1.mol

Synonyms:4-fluoro-1-benzylbenzene;1-benzyl--4-fluorobenzene;

Chemical Property of 4-FLUORODIPHENYLMETHANE

Chemical Property:

• Refractive Index: 1.5540 to 1.5580
• Boiling Point: 94°C 1mm
• PSA: 0.00000
• Density: 1
• LogP: 3.41650

Purity/Quality:

97% ^*data from raw suppliers

4-Fluorodiphenylmethane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-FLUORODIPHENYLMETHANE

There total 110 articles about 4-FLUORODIPHENYLMETHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-chloromethyl-4-fluorobenzene (352-11-4) + phenylboronic acid (98-80-6) → 4-fluorodiphenylmethane (587-79-1)

Guidance literature:

With potassium phosphate; SP-4-[1,3-bis[2,6-diisopropylphenyl]-1,3-dihydro-2H-imidazol-2-ylidene]chloro[2-(1-methyl-1H-imidazol-2-yl-κN³)phenyl-κC]palladium(II); In ethanol; at 60 ℃; for 2h; Inert atmosphere;

DOI:10.1021/om5004336

Reference yield: 99.0%

4-fluoroboronic acid (1765-93-1) + benzyl chloride (100-44-7) → 4-fluorodiphenylmethane (587-79-1)

Guidance literature:

With potassium phosphate; SP-4-[1,3-bis[2,6-diisopropylphenyl]-1,3-dihydro-2H-imidazol-2-ylidene]chloro[2-(1-methyl-1H-imidazol-2-yl-κN³)phenyl-κC]palladium(II); In ethanol; at 60 ℃; for 2h; Inert atmosphere;

DOI:10.1021/om5004336

Reference yield: 91.0%

4-fluoroboronic acid (1765-93-1) + benzyl bromide (100-39-0) → 4-fluorodiphenylmethane (587-79-1)

Guidance literature:

With sodium carbonate; trans-PdBr(N-Succ)(PPh₃)2; In tetrahydrofuran; at 60 ℃; for 2h;

DOI:10.1021/ol702291r

upstream raw materials:

1-chloromethyl-4-fluorobenzene

benzene

4-fluorobenzophenone

4-fluorobenzhydrol

Downstream raw materials:

1-[4-(4-fluorobenzyl)phenyl]ethan-1-one

Diphenylmethane

4-[2-(4-Fluoro-phenyl)-2-phenyl-ethyl]-1H-imidazole

2,2,2-trichloroethyl 4-fluorobenzhydrylcarbamate