Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-

Base Information

Chemical Name:Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-
CAS No.:58907-90-7
Molecular Formula:C₁₂H₁₅NO
Molecular Weight:189.257
Hs Code.:
DSSTox Substance ID:DTXSID30482754
Nikkaji Number:J2.658.958D

Synonyms:58907-90-7;Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-;DTXSID30482754

Suppliers and Price of Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:189.115364102
Heavy Atom Count:14
Complexity:201

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2N(C1)CC(O2)C3=CC=CC=C3

Technology Process of Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl-

There total 4 articles about Pyrrolo[2,1-b]oxazole, hexahydro-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22081-44-3
N-(2-hydroxy-2-phenylethyl)pyrrodidin-2-one

: 58907-90-7
2-phenyl-hexahydro-pyrrolo[2,1-b]oxazole

: 5407-61-4
1-phenyl-2-(pyrrolidin-1-yl)ethanol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -70 ℃; for 1h; Title compound not separated from byproducts;

Reference yield:

: 5407-61-4
1-phenyl-2-(pyrrolidin-1-yl)ethanol

: 58907-90-7
2-phenyl-hexahydro-pyrrolo[2,1-b]oxazole

: 22081-44-3
N-(2-hydroxy-2-phenylethyl)pyrrodidin-2-one

Guidance literature:: With triphenylfluoroborate; In acetonitrile; for 24h; Title compound not separated from byproducts; Heating;

Reference yield:

: 5407-61-4
1-phenyl-2-(pyrrolidin-1-yl)ethanol

: 58907-90-7
2-phenyl-hexahydro-pyrrolo[2,1-b]oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 6 percent Chromat_. / triphenylcarbeniumfluoroborate / acetonitrile / 24 h / Heating

2: 11 percent Chromat_. / diisobuthylaluminiumhydride / CH₂Cl₂; toluene / 1 h / -70 °C

With trityl tetrafluoroborate; diisobutylaluminium hydride; In dichloromethane; toluene; acetonitrile;