Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]-

Base Information

Chemical Name:Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]-
CAS No.:59120-86-4
Molecular Formula:C17H11NO
Molecular Weight:245.28
Hs Code.:

Synonyms:

Suppliers and Price of Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]-

There total 5 articles about Benzonitrile, 4-[(E)-(1,3-dihydro-1-oxo-2H-inden-2-ylidene)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 61436-73-5
2-allylbenzoic acid

: 623-00-7
4-bromobenzenecarbonitrile

: 59120-86-4
4-[(2,3-dihydro-1-oxo-1H-inden-2-ylidene)methyl]benzonitrile

Guidance literature:: 2-allylbenzoic acid; With palladium diacetate; acetic anhydride; tris-(o-tolyl)phosphine; In tetrahydrofuran; at 65 ℃; for 18h; Inert atmosphere;

4-bromobenzenecarbonitrile; With tributyl-amine; In N,N-dimethyl-formamide; at 120 ℃; Inert atmosphere;
DOI:10.1002/chem.201403561

Reference yield: 49.05%

: 83-33-0
inden-1-one

: 105-07-7
4-cyanobenzaldehyde

: 59120-86-4
4-[(2,3-dihydro-1-oxo-1H-inden-2-ylidene)methyl]benzonitrile

Guidance literature:: With potassium hydroxide; In methanol; at 20 ℃; for 0.5h;
DOI:10.1002/hlca.200690028

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 59120-86-4
4-[(2,3-dihydro-1-oxo-1H-inden-2-ylidene)methyl]benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid; sodium nitrite / water / 0.5 h / 5 °C / Inert atmosphere

1.2: 1 h / 100 °C / Inert atmosphere

2.1: methylmagnesium bromide / tetrahydrofuran / 0.08 h / -30 °C / Inert atmosphere

2.2: 1 h / -30 °C / Inert atmosphere

3.1: acetic anhydride; palladium diacetate; tris-(o-tolyl)phosphine / tetrahydrofuran / 18 h / 65 °C / Inert atmosphere

3.2: 120 °C / Inert atmosphere

With sulfuric acid; methylmagnesium bromide; palladium diacetate; acetic anhydride; tris-(o-tolyl)phosphine; sodium nitrite; In tetrahydrofuran; water; 1.1: |Sandmeyer Reaction / 3.1: |Heck Reaction;
DOI:10.1002/chem.201403561