2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride

Base Information

Chemical Name:2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride
CAS No.:73426-04-7
Molecular Formula:C₂₀H₂₂N₂S*ClH
Molecular Weight:358.935
Hs Code.:
DSSTox Substance ID:DTXSID00994177

Synonyms:2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride;Thiopyrano(2,3-b)indole-4-methanamine, 2,3,4,9-tetrahydro-N-ethyl-9-phenyl-, monohydrochloride;73426-04-7;C20H22N2S.ClH;DTXSID00994177;LS-153265;N-[(9-Phenyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indol-4-yl)methyl]ethanamine--hydrogen chloride (1/1)

Suppliers and Price of 2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride

Chemical Property:

Vapor Pressure:3.46E-09mmHg at 25°C
Boiling Point:474.9°Cat760mmHg
Flash Point:241°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:358.1270476
Heavy Atom Count:24
Complexity:382

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNCC1CCSC2=C1C3=CC=CC=C3N2C4=CC=CC=C4.Cl

Technology Process of 2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride

There total 3 articles about 2,3,4,9-Tetrahydro-N-ethyl-9-phenylthiopyrano(2,3-b)indole-4-methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73425-20-4
1-phenylindoline-2-thione

: 73426-04-7
4-(N-ethylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / K₂CO₃

2: toluene; pyridine / 0.5 h / Heating

3: 58 percent / 1) NaBH₄; 2) HCl

With hydrogenchloride; sodium tetrahydroborate; potassium carbonate; In pyridine; toluene;
DOI:10.1248/cpb.32.877

Reference yield:

: 3335-98-6
1-phenyl-1,3-dihydro-indol-2-one

: 73426-04-7
4-(N-ethylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / P₂S₅, NaHCO₃ / tetrahydrofuran / 3 h / Ambient temperature

2: 95 percent / K₂CO₃

3: toluene; pyridine / 0.5 h / Heating

4: 58 percent / 1) NaBH₄; 2) HCl

With hydrogenchloride; sodium tetrahydroborate; tetraphosphorus decasulfide; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; pyridine; toluene;
DOI:10.1248/cpb.32.877

Reference yield:

: 73425-21-5
4-hydroxybut-2-ynyl 1-phenylindol-2-yl sulfide

: 73426-04-7
4-(N-ethylaminomethyl)-9-phenyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: toluene; pyridine / 0.5 h / Heating

2: 58 percent / 1) NaBH₄; 2) HCl

With hydrogenchloride; sodium tetrahydroborate; In pyridine; toluene;
DOI:10.1248/cpb.32.877