N-[4-(4-methoxyphenyl)butyl]acetamide

Base Information

Chemical Name:N-[4-(4-methoxyphenyl)butyl]acetamide
CAS No.:59181-31-6
Molecular Formula:C13H19NO2
Molecular Weight:221.299
Hs Code.:
DSSTox Substance ID:DTXSID90441761
Wikidata:Q82258685
ChEMBL ID:CHEMBL50577

Synonyms:CHEMBL50577;N-[4-(4-methoxyphenyl)butyl]acetamide;59181-31-6;DTXSID90441761;BDBM50471035

Suppliers and Price of N-[4-(4-methoxyphenyl)butyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(4-methoxyphenyl)butyl]acetamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:221.141578849
Heavy Atom Count:16
Complexity:198

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NCCCCC1=CC=C(C=C1)OC

Technology Process of N-[4-(4-methoxyphenyl)butyl]acetamide

There total 8 articles about N-[4-(4-methoxyphenyl)butyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 72457-26-2
4-(4-Methoxyphenyl)butylamine

: 108-24-7
acetic anhydride

: 59181-31-6
N-[4-(4-Methoxy-phenyl)-butyl)-acetamid

Guidance literature:: With triethylamine; In dichloromethane; for 2h; Ambient temperature;

Reference yield:

: 4521-28-2
4-(4-Methoxyphenyl)butyric acid

: 59181-31-6
N-[4-(4-Methoxy-phenyl)-butyl)-acetamid

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 3 h / Heating

2: aq. ammonia / 0.5 h / 0 °C

3: 14 percent / LiAlH₄ / CH₂Cl₂; tetrahydrofuran / 96 h / Heating

4: NEt₃ / CH₂Cl₂ / 3 h / Ambient temperature

With ammonium hydroxide; lithium aluminium tetrahydride; thionyl chloride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/(SICI)1521-4184(199812)331:12<395::AID-ARDP395>3.0.CO;2-7

Reference yield:

: 2222-15-3
4-(4-Methoxyphenyl)-butyramide

: 59181-31-6
N-[4-(4-Methoxy-phenyl)-butyl)-acetamid

Guidance literature:: Multi-step reaction with 2 steps

1: 14 percent / LiAlH₄ / CH₂Cl₂; tetrahydrofuran / 96 h / Heating

2: NEt₃ / CH₂Cl₂ / 3 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/(SICI)1521-4184(199812)331:12<395::AID-ARDP395>3.0.CO;2-7