1-(2-Chlorobenzyl)piperidine

Base Information

Chemical Name:1-(2-Chlorobenzyl)piperidine
CAS No.:59507-48-1
Molecular Formula:C12H16ClN
Molecular Weight:209.719
Hs Code.:
ChEMBL ID:CHEMBL3113393
DSSTox Substance ID:DTXSID50482635
Wikidata:Q82319166
Mol file:59507-48-1.mol

Synonyms:1-(2-chlorobenzyl)piperidine;59507-48-1;1-[(2-chlorophenyl)methyl]piperidine;Piperidine, 1-[(2-chlorophenyl)methyl]-;SCHEMBL3210628;CHEMBL3113393;DTXSID50482635;AKOS003974663;CS-0271829;EN300-1197066

Suppliers and Price of 1-(2-Chlorobenzyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
1-(2-CHLOROBENZYL)PIPERIDINE
1g
$ 809.00

Rieke Metals
1-(2-CHLOROBENZYL)PIPERIDINE
5g
$ 1943.00

Crysdot
1-(2-Chlorobenzyl)piperidine 97%
5g
$ 1177.00

Crysdot
1-(2-Chlorobenzyl)piperidine 97%
1g
$ 437.00

Total 4 raw suppliers

Chemical Property of 1-(2-Chlorobenzyl)piperidine

Chemical Property:

PSA：3.24000
LogP:3.26380
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:209.0971272
Heavy Atom Count:14
Complexity:166

Purity/Quality:

99% ^*data from raw suppliers

1-(2-CHLOROBENZYL)PIPERIDINE ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CC2=CC=CC=C2Cl

Technology Process of 1-(2-Chlorobenzyl)piperidine

There total 4 articles about 1-(2-Chlorobenzyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 110-89-4
piperidine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 615-41-8
2-iodochlorobenzene

: 59507-48-1
1-(2-chlorobenzyl)piperidine

Guidance literature:: With cobalt(II) bromide; zinc; In acetonitrile; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1055/s-0029-1217108

Reference yield: 67.0%

: 110-89-4
piperidine

: 611-17-6
1-bromomethyl-2-chlorobenzene

: 59507-48-1
1-(2-chlorobenzyl)piperidine

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 0.25h;

Reference yield: 48.0%

: 110-89-4
piperidine

: 89-98-5
2-chloro-benzaldehyde

: 59507-48-1
1-(2-chlorobenzyl)piperidine

Guidance literature:: With 2,6-dimethylbenzene-1-thiol; boron trioxide; Ir(dF(CF₃)ppy)2(bpy)PF₆; In acetonitrile; at 25 - 27 ℃; for 24h; chemoselective reaction; Sealed tube; Inert atmosphere; Irradiation;
DOI:10.1021/acs.orglett.8b00895