2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)-

Base Information

Chemical Name:2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)-
CAS No.:59817-20-8
Molecular Formula:C17H17NO2
Molecular Weight:267.32200
Hs Code.:

Synonyms:trans-4'-dimethylamino-2-hydroxychalcone;2-Propen-1-one,1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl);2-hydroxy-4'-(dimethylamino)chalcone;1-(4-dimethylaminophenyl)-3-(2-hydroxyphenyl)-2-propen-1-one;

Suppliers and Price of 2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)-

Chemical Property:

Boiling Point:464.1±45.0 °C(Predicted)
PSA：40.54000
Density:1.181±0.06 g/cm3(Predicted)
LogP:3.35430

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)-

There total 4 articles about 2-Propen-1-one, 1-[4-(dimethylamino)phenyl]-3-(2-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 131684-09-8
1-(4-(dimethylamino)phenyl)-2-(triphenyl-λ⁵-phosphaneylidene)ethan-1-one

: 90-02-8
salicylaldehyde

: 59817-20-8
(E)-1-(4'-(dimethylamino)phenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: In chloroform; for 16h; Reflux;
DOI:10.1039/c6ob01326k

Reference yield:

: 2124-31-4
4'-dimethylaminoacetophenone

: 59817-20-8
(E)-1-(4'-(dimethylamino)phenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: bromine; hydrogen bromide / 0 - 25 °C

2: tetrahydrofuran / 4 h / Reflux

3: chloroform / 16 h / Reflux

With hydrogen bromide; bromine; In tetrahydrofuran; chloroform;
DOI:10.1039/c6ob01326k

Reference yield:

: 37904-72-6
2-bromo-1-(4-(dimethylamino)phenyl)ethanone

: 59817-20-8
(E)-1-(4'-(dimethylamino)phenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 4 h / Reflux

2: chloroform / 16 h / Reflux

In tetrahydrofuran; chloroform;
DOI:10.1039/c6ob01326k