2124-31-4

Basic information

• Product Name: 4'-DIMETHYLAMINOACETOPHENONE
• Synonyms: 4'-DIMETHYLAMINOACETOPHENONE;4'-(N,N-DIMETHYLAMINO)ACETOPHENONE;4-(N,N-DIMETHYLAMINO)ACETOPHENONE;TIMTEC-BB SBB007875;P-(DIMETHYLAMINO)ACETOPHENONE;1-(4-Dimethylamino-phenyl)-ethanone;1-[4-(dimethylamino)phenyl]-ethanon;1-[4-(Dimethylamino)phenyl]ethanone
• CAS NO: 2124-31-4
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Product Categories: Amines;blocks;Aromatic Acetophenones & Derivatives (substituted);Benzene series
• Mol File: 2124-31-4.mol
• Article Data: 67

Chemical Properties

• Melting Point: 105°C
• Boiling Point: 282.9 °C at 760 mmHg
• Flash Point: 107 °C
• Appearance: /
• Density: 1.026 g/cm³
• Vapor Pressure: 0.00327mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.16±0.12(Predicted)
• CAS DataBase Reference: 4'-DIMETHYLAMINOACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-DIMETHYLAMINOACETOPHENONE(2124-31-4)
• EPA Substance Registry System: 4'-DIMETHYLAMINOACETOPHENONE(2124-31-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2124-31-4(Hazardous Substances Data)

Usage

Chemical Properties

off-white crystalline powder

Uses

4''-Dimethylaminoacetophenone

InChI:InChI=1/C10H13NO/c1-8(12)9-4-6-10(7-5-9)11(2)3/h4-7H,1-3H3

Upstream product

• 108-24-7 acetic anhydride 
• 121-69-7 N,N-dimethyl-aniline 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 50-00-0 formaldehyd 
• 99-92-3 p-aminobenzophenone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 79-16-3 N-methyl-acetamide 
• 463-51-4 Ketene 
• 127-19-5 N,N-dimethyl acetamide 
• 3847-19-6 2-acetoxypyridine 
• 320349-36-8 C₁₀H₁₄NO 
• 880142-29-0 trans-α-bromo-4-dimethylamino-cinnamic acid 
• 75-36-5 acetyl chloride 

Downstream Products

• 1681-94-3 4-dimethylaminochalcone 
• 105905-95-1 (4-dimethylamino-phenyl)-thioacetic acid dimethylamide 
• 111241-31-7 3-ethyl-2-[2-(4-dimethylamino-phenyl)-propenyl]-benzothiazolium; iodide 
• 111528-52-0 2-[2-(4-dimethylamino-phenyl)-propenyl]-3-methyl-benzothiazolium; iodide 
• 113062-19-4 2-(4-dimethylamino-phenyl)-3-(4-methoxy-phenyl)-butane-2,3-diol 
• 4150-37-2 N,N-dimethyl-4-ethylaniline 
• 54441-61-1 ethyl 3-(4-(dimethylamino)phenyl)-3-oxopropanoate 
• 37904-72-6 2-bromo-1-(4-(dimethylamino)phenyl)ethanone 
• 114890-27-6 2,3-bis-(4-dimethylamino-phenyl)-butane-2,3-diol 
• 140885-44-5 1-<4-(Dimethylamino)phenyl>-3-(2-furyl)prop-2-en-1-one 
• 127034-48-4 1-(4-(dimethylamino)phenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 

Relevant articles and documents

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Cooperative electron transfer fragmentation reactions. Amplification of a photoreaction through a tandem chain fragmentation of acceptor and donor pinacols

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NHC ligand-based half-sandwich iridium complexes: synthesis, structure and catalytic activity in acceptorless dehydrogenation and transfer hydrogenation

A set of neutral C,C-chelate half-sandwich iridium(iii) complexes have been prepared with NHC ligands that contain pendant aromatic rings as potentially chelating donor sites. The catalytic activity of such iridium complexes has been investigated for the acceptorless dehydrogenation (AD) reactions of alcohols and for the transfer hydrogenation reactions of ketones. The prepared iridium(iii) complexes show excellent catalytic activity for AD reactions of a wide range of secondary alcohols, and they are also shown to be effective for the synthesis of aldehydes from primary alcohols without the observation of undesired byproducts such as esters. Additionally, these complexes are also highly efficient in transfer hydrogenation of ketones and aldehydes, which give the alcohols in good yields under mild conditions. The exact structure and bonding mode of the NHC-based iridium complexes was identified using various spectroscopic methods and single crystal X-ray analysis.

Ruthenium-Catalyzed Dehydrogenation of Alcohols with Carbodiimide via a Hydrogen Transfer Mechanism

Ruthenium-catalyzed oxidative dehydrogenation of alcohols using carbodiimide as an efficient hydrogen acceptor has been developed. The protocol exhibits wide substrate scope with good to excellent yields. The results of the kinetic analysis indicated that the reaction mechanism includes the hydrogen transfer process and that the addition of carbodiimide is essential for the reaction system, and the resulting amidine also could react as a hydrogen acceptor.