1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

Base Information

Chemical Name:1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-
CAS No.:152537-57-0
Molecular Formula:C₁₁H₁₇N₅O₃S
Molecular Weight:299.354
Hs Code.:
DSSTox Substance ID:DTXSID20165049
Nikkaji Number:J842.328H
Wikidata:Q83034189

Synonyms:1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-;152537-57-0;2,2-Dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-1-propanesulfonamide;2,2-dimethyl-3-[(7-methyl-[1,2,4]triazolo[1,5-b]pyridazin-6-yl)oxy]propane-1-sulfonamide;SCHEMBL7832334;C11H17N5O3S;DTXSID20165049;C11-H17-N5-O3-S;LS-120921

Suppliers and Price of 1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.46g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:299.10521059
Heavy Atom Count:20
Complexity:436

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=NC=NN2N=C1OCC(C)(C)CS(=O)(=O)N

Technology Process of 1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

There total 4 articles about 1-Propanesulfonamide, 2,2-dimethyl-3-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51519-27-8
6-chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazine

1N-hydrochloric acid: 1N-hydrochloric acid

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 132115-56-1
3-hydroxy-2,2-dimethyl-1-propanesulfonamide

: 152537-57-0
6-(2,2-dimethyl-3-sulfamoyl-1-propoxy)-7-methyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:: In tetrahydrofuran; N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

Reference yield:

: 66346-87-0
6-chloro-5-methylpyridazin-3-amine

: 152537-57-0
6-(2,2-dimethyl-3-sulfamoyl-1-propoxy)-7-methyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: toluene

2: 1.) NH₂OH*HCl, 2.) polyphosphoric acid

3: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, 18 h

With PPA; hydroxylamine hydrochloride; sodium hydride; In toluene;
DOI:10.1248/cpb.45.1447

Reference yield:

: 51519-07-4
N’-(6-chloro-5-methylpyridazin-3-yl)-N,N-dimethylformimidamide

: 152537-57-0
6-(2,2-dimethyl-3-sulfamoyl-1-propoxy)-7-methyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NH₂OH*HCl, 2.) polyphosphoric acid

2: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, 18 h

With PPA; hydroxylamine hydrochloride; sodium hydride;
DOI:10.1248/cpb.45.1447