6-Chloro-5-methylpyridazin-3-amine

Base Information

• Chemical Name: 6-Chloro-5-methylpyridazin-3-amine
• CAS No.: 66346-87-0
• Molecular Formula: C5H6ClN3
• Molecular Weight: 143.5742
• Hs Code.: 2933990090
• European Community (EC) Number: 820-228-1
• DSSTox Substance ID: DTXSID90493523
• Nikkaji Number: J1.208.561C
• Wikidata: Q82340263
• Mol file: 66346-87-0.mol

Synonyms:6-CHLORO-5-METHYLPYRIDAZIN-3-AMINE;66346-87-0;6-amino-3-chloro-4-methylpyridazine;3-amino-6-chloro-5-methylpyridazine;C5H6ClN3;MFCD19203420;3-Pyridazinamine, 6-chloro-5-methyl-;6-chloro-5-methyl-3-pyridazinamine;SCHEMBL103038;AMY5291;DTXSID90493523;UWDLNRUFHRYMSE-UHFFFAOYSA-N;BCP28935;AKOS006342373;6-Chloro-5-methyl-pyridazin-3-ylamine;CS-W018589;SB18623;DS-15882;SY014811;FT-0747648;A23604;P12525

Chemical Property of 6-Chloro-5-methylpyridazin-3-amine

Chemical Property:

• Melting Point: 190-191 °C(Solv: ethanol (64-17-5))
• Boiling Point: 358.423 °C at 760 mmHg
• PKA: 4.98±0.10(Predicted)
• Flash Point: 170.569 °C
• PSA: 51.80000
• Density: 1.35 g/cm³
• LogP: 1.60180
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 143.0250249
• Heavy Atom Count: 9
• Complexity: 98.2

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-5-methylpyridazin-3-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NN=C1Cl)N
• Uses: 6-CHLORO-5-METHYLPYRIDAZIN-3-AMINE is a useful research chemical.

Technology Process of 6-Chloro-5-methylpyridazin-3-amine

There total 5 articles about 6-Chloro-5-methylpyridazin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(6-chloro-5-methyl-pyridazin-3-yl)-(2,4-dimethoxy-benzyl)-amine → 6-chloro-5-methylpyridazin-3-amine (66346-87-0)

Guidance literature:

With trifluoroacetic acid; at 20 ℃;

Reference yield: 72.7%

3,6-dichloro-4-methylpyridazine (19064-64-3) → 6-chloro-5-methylpyridazin-3-amine (66346-87-0)

Guidance literature:

With ammonia; In ethanol; water; at 100 ℃; for 48h;

Reference yield: 43.5%

3,6-dichloro-4-methylpyridazine (19064-64-3) → 6-chloro-5-methylpyridazin-3-amine (66346-87-0) + 3-amino-6-chloro-4-methylpyridazine (64068-00-4)

Guidance literature:

With ammonia; In ethanol; at 120 ℃; for 12h; Heating in a sealed tube;

upstream raw materials:

3,6-dichloro-4-methylpyridazine

(6-chloro-5-methylpyridazin-3-yl)hydrazine

Downstream raw materials:

4-amino-N-(6-chloro-5-methyl-pyridazin-3-yl)-benzenesulfonamide

6-Chloro-7-methyl-2-phenyl-5H-imidazo[1,2-b]pyridazin-3-one

(6-chloro-7-methyl-2-phenyl-imidazo[1,2-b]pyridazin-3-yl)-acetic acid ethyl ester

6-chloro-7-methyl-2-phenylimidazo[1,2-b]pyridazine